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Safety Information

80337

Supelco

(±)-Metoprolol (+)-tartrate salt

analytical standard

Synonym(s):

(±)1-(Isopropylamino)-3-[p-(β-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt, Lopressor

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About This Item

Linear Formula:
(C15H25NO3)2 · C4H6O6
CAS Number:
56392-17-7
Molecular Weight:
684.81
EC Number:
260-148-9
MDL number:
MFCD00056257
UNSPSC Code:
41116107
PubChem Substance ID:
329768801
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤1.0% water

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.COCCc1ccc(OCC(O)CNC(C)C)cc1.COCCc2ccc(OCC(O)CNC(C)C)cc2

InChI

1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;;1-,2-/m..1/s1

InChI key

YGULWPYYGQCFMP-CEAXSRTFSA-N

Gene Information

human ... ADRB1(153)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardEnvironment
GHS08,GHS09

Signal Word

Warning

Hazard Statements

H361d,H411

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

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V M Raju et al.
Clinical radiology, 69(7), 739-744 (2014-05-16)
To evaluate the usage, safety, and efficacy of high-dose intravenous metoprolol for heart rate reduction in computer tomographic (CT) coronary angiography. As this was retrospective analysis of anonymous data, medical ethics committee approval was waived by the regional health research
Reply: Carvedilol versus metoprolol, but which metoprolol? Effect on inappropriate cardioverter-defibrillator therapy.
Martin H Ruwald et al.
Journal of the American College of Cardiology, 63(18), 1933-1934 (2014-02-04)
Abdulhakim A A Khaled et al.
Acta poloniae pharmaceutica, 70(5), 873-875 (2013-10-24)
The aim of this article was to assess and apply the in vitro to in vivo profiling (IVIVP), a new biowaiver approach, in designing a product with specific release pattern. The IVIVP was established by plotting the observed and predicted
Wenhuan Li et al.
Medicine, 93(28), e329-e329 (2014-12-20)
The sensitivity and specificity of 5 different image sets of dual-energy computed tomography (DECT) for the detection of first-pass myocardial perfusion defects have not systematically been compared using positron emission tomography (PET) as a reference standard. Forty-nine consecutive patients, with
S Veloutsou et al.
Chemosphere, 107, 180-186 (2014-03-05)
Active pharmaceutical compounds reach the wastewater treatment plants mainly through excretion and improper disposal, and, because of insufficient treating methods, they end up to surface water or even potable water in some cases. Atenolol and metoprolol are β-blockers, members of
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