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Safety Information

76850

Sigma-Aldrich

1,2,2,6,6-Pentamethylpiperidine

purum, ≥99.0% (GC)

Synonym(s):

PMP, Pempidine

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About This Item

Empirical Formula (Hill Notation):
C10H21N
CAS Number:
Molecular Weight:
155.28
Beilstein:
103806
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

grade

purum

Assay

≥99.0% (GC)

refractive index

n20/D 1.460 (lit.)
n20/D 1.460

bp

187-188 °C (lit.)

density

0.858 g/mL at 25 °C (lit.)

SMILES string

CN1C(C)(C)CCCC1(C)C

InChI

1S/C10H21N/c1-9(2)7-6-8-10(3,4)11(9)5/h6-8H2,1-5H3

InChI key

XULIXFLCVXWHRF-UHFFFAOYSA-N

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Other Notes

One of the most strongly basic tertiary amines (sterically hindered and nonquaternizing)

Pictograms

FlameSkull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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H.Z. Sommer et al.
The Journal of Organic Chemistry, 36, 824-824 (1971)
M L Kemel et al.
Neuroscience, 50(3), 597-610 (1992-10-01)
Previously, using a new in vitro microsuperfusion procedure, we have demonstrated marked differences in the cholinergic presynaptic regulation of the release of [3H]dopamine continuously synthesized from [3H]tyrosine in two close striosomal- and matrix-enriched areas of the cat caudate nucleus. A
[Tuberculous osteoarthritis revealed by ankle injury].
O Louletzian et al.
Presse medicale (Paris, France : 1983), 28(10), 531-532 (1999-04-21)
L Tremblay et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(23), 11214-11218 (1992-12-01)
Using a sensitive in vitro microperfusion method, the effects of selective and potent agonists of NK1, NK2, and NK3 tachykinin receptors ([Pro9]SP, ([Lys5,MeLeu9,Nle10]NKA-(4-10), and [Pro7]NKB, respectively) on the presynaptic control of dopamine release were investigated in striosomal-enriched (area rich in
D Blozovski
Developmental psychobiology, 18(4), 355-366 (1985-07-01)
Young rats, 11, 16, and 20 days of age, received bilateral injections of three antinicotinic agents into the posteroventral hippocampo-subiculo-entorhinal area, and were trained to learn a cool-draft-stimulus, passive-avoidance task shortly after (17 min). Gallamine triethiodide had no action at

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