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Merck
CN

76163

4-Methylumbelliferyl palmitate

≥98.0% (TLC)

Synonym(s):

Palmitic acid 4-methylumbelliferyl ester

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About This Item

Empirical Formula (Hill Notation):
C26H38O4
CAS Number:
17695-48-6
Molecular Weight:
414.58
EC Number:
241-695-2
UNSPSC Code:
12352200
PubChem Substance ID:
24886951
Beilstein/REAXYS Number:
4884046
MDL number:
MFCD00037612

Key Documents

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InChI key

QKQVFFACWLFRRX-UHFFFAOYSA-N

InChI

1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3

SMILES string

CCCCCCCCCCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1

assay

≥98.0% (TLC)

mp

77 °C (lit.)

solubility

2-methoxyethanol: soluble, chloroform: soluble

fluorescence

λex 360 nm; λem 449 nm in 0.1 M phosphate pH 8.0

suitability

suitable for fluorescence

storage temp.

−20°C

Application

Fluorogenic substrate for acid lipase in human leukocytes.
suitable as fluorogenic substrate for lipases

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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S Kelly et al.
Clinica chimica acta; international journal of clinical chemistry, 97(2-3), 239-242 (1979-10-01)
A fluorimetric assay for leukocyte acid lipase, the enzyme defect in Wolman disease, is described. The method requires a smaller volume of blood and can be performed more rapidly than the present colorimetric assay for the leukocyte enzyme.
M W Baillargeon et al.
Lipids, 26(10), 831-836 (1991-10-01)
Lipases from Geotrichum candidum NRRL Y-553 are of interest because of their unique specificity for cis-9-unsaturated fatty acids relative to both stearic and palmitic acids. The lipases were partially purified by chromatography on Octyl Sepharose, AG MP-1 macroporous anion exchanger

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