74530
L-(−)-Norephedrine
purum, ≥98.0% (NT)
Synonym(s):
(1R,2S)-2-Amino-1-phenyl-1-propanol
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About This Item
Empirical Formula (Hill Notation):
C9H13NO
CAS Number:
Molecular Weight:
151.21
PubChem Substance ID:
UNSPSC Code:
12352000
NACRES:
NA.22
EC Number:
207-755-7
MDL number:
Beilstein/REAXYS Number:
2207678
SMILES string
C[C@H](N)[C@H](O)c1ccccc1
grade
purum
assay
≥98.0% (NT)
optical activity
[α]20/D −41.0±1°, c = 7% in 1 M HCl
storage temp.
2-8°C
Gene Information
rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413)
Regulatory Information
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Carlos Castillo-Henkel et al.
Proceedings of the Western Pharmacology Society, 53, 33-36 (2010-01-01)
Here we contrast the vascular smooth muscle contractility produced by D-nor-pseudoephedrine, alone or combined with triiodothyronine, on the aorta and coronary vasculature of the rat. At high concentrations (greater than those found in normal therapeutic dosing) D-nor-pseudoephedrine contracted the aorta.
Hyeon-Kyu Lee et al.
The Journal of organic chemistry, 77(12), 5454-5460 (2012-05-25)
Each of the enantiomers of both norephedrine and norpseudoephedrine were stereoselectively prepared from the common, prochiral cyclic sulfamidate imine of racemic 1-hydroxy-1-phenyl-propan-2-one by employing asymmetric transfer hydrogenation (ATH) catalyzed by the well-defined chiral Rh-complexes, (S,S)- or (R,R)-Cp*RhCl(TsDPEN), and HCO(2)H/Et(3)N as
Saba Kassim et al.
Journal of ethnopharmacology, 140(1), 193-196 (2012-01-17)
Khat chewing amongst the UK communities originating from Yemen and the East African coast is suggested to create dependency through its main stimulant components (cathinone, norephedrine and norpseudoephedrine) on the central nervous system. To validate self-reported khat chewing behaviours by
Richard Hoffman et al.
Journal of ethnopharmacology, 132(3), 554-563 (2010-06-18)
Although there is a rich body of research available regarding the effect of acute and chronic khat dosing in animal models, research on the behavioral and cognitive effects of khat in human subjects is not extensive and several of the
Raz Krizevski et al.
Journal of ethnopharmacology, 114(3), 432-438 (2007-10-12)
Khat (Catha edulis Forsk., Celastraceae) is a perennial shrub that was introduced to Israel by Yemenite immigrants. Khat young leaves are chewed as a stimulant. The main stimulating active principles in this plant are the phenylpropylamino alkaloids (-)-cathinone [(S)-alpha-aminopropiophenone], (+)-cathine
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