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69532

Supelco

Artemisinin

analytical standard

Synonym(s):

Arteannuin, Qinghaosu

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About This Item

Empirical Formula (Hill Notation):
C15H22O5
CAS Number:
63968-64-9
Molecular Weight:
282.33
MDL number:
MFCD00081057
UNSPSC Code:
41116107
PubChem Substance ID:
329761732
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (TLC)

optical activity

[α]/D +75.0±3°, c = 0.5 in methanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

156-157 °C (lit.)

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3OC4(C)CC[C@@H]1[C@@]23OO4

InChI

1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key

BLUAFEHZUWYNDE-NNWCWBAJSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Lot/Batch Number

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Moran Farhi et al.
Biotechnology & genetic engineering reviews, 29, 135-148 (2014-02-27)
Artemisinin, a natural compound from Artemisia annua, is highly effective in treating drug-resistant malaria. Because chemical synthesis of this natural terpenoid is not economically feasible, its only source remains as the native plant which produces only small quantities of it
Nicholas M Njuguna et al.
Expert opinion on therapeutic patents, 22(10), 1179-1203 (2012-09-14)
The isolation of artemisinin from an ancient Chinese remedy in the early 1970s heralded the beginning of a new era in antimalarial drug therapy culminating in artemisinin-based combination therapies currently being the mainstay of malaria treatment worldwide. Ongoing research on
Debashish Das et al.
Malaria journal, 12, 125-125 (2013-04-23)
Parasitaemia on Day 3 has been proposed as a useful alert of potential artemisinin resistance, however, the normal variation of parasite clearance observed in artemisinin-based combination therapy clinical trials is poorly documented. The trends in early parasitological response following treatment
Rick M Fairhurst et al.
The American journal of tropical medicine and hygiene, 87(2), 231-241 (2012-08-03)
Artemisinin-based combination therapies are the most effective drugs to treat Plasmodium falciparum malaria. Reduced sensitivity to artemisinin monotherapy, coupled with the emergence of parasite resistance to all partner drugs, threaten to place millions of patients at risk of inadequate treatment
Sanjeev Krishna et al.
Trends in parasitology, 29(7), 313-317 (2013-04-30)
The definition of artemisinin resistance is becoming one of a prolonged parasite clearance phenotype, although this variable is a complex function of both host and parasite characteristics. We discuss some of the limitations of this definition of artemisinin resistance, particularly
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