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Merck
CN

68878

(+)-Borneol

analytical standard

Synonym(s):

endo-(1R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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About This Item

Empirical Formula (Hill Notation):
C10H18O
CAS Number:
464-43-7
Molecular Weight:
154.25
Beilstein:
2038056
EC Number:
208-080-0
MDL number:
MFCD00066427
UNSPSC Code:
85151701
PubChem Substance ID:
329761192
NACRES:
NA.24

Key Documents

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grade

analytical standard

Quality Level

100

Assay

≥97.5% (GC)

optical activity

[α]20/D 37.0±2.0°, c = 5 in ethanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

206-209 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

[H][C@@]12CC[C@@](C)([C@@H](O)C1)C2(C)C

InChI

1S/C10H18O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7-8,11H,4-6H2,1-3H3/t7-,8+,10+/m1/s1

InChI key

DTGKSKDOIYIVQL-WEDXCCLWSA-N

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General description

Borneol, a bicyclic monoterpenoid alcohol which is a major constituent of medicinal plants is grouped under the volatile organic compounds (VOCs) family of chemicals. It is employed as analgesic and anesthetic in traditional Chinese and Japanese medicines.

Application

(+)-Borneol has been reported exert highly efficient positive modulating gamma-aminobutyric action (GABA) action at human recombinant α1β2γ2L GABAA receptors.
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Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: angelica cinnamomum curcuma echinacea salvia thymus valeriana zingiber

Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H228

Precautionary Statements

P210

Hazard Classifications

Flam. Sol. 2

Storage Class Code

4.1B - Flammable solid hazardous materials

WGK

WGK 3

Flash Point(F)

149.0 °F - closed cup

Flash Point(C)

65 °C - closed cup

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
0000232161
0000232161
0000191236
0000188086
0000186727

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The enhancing effect of synthetical borneol on the absorption of tetramethylpyrazine phosphate in mouse.
Yan-Yu X, et al.
International Journal of Pharmaceutics, 337(1-2), 74-79 (2007)
Supercritical carbon dioxide extraction of volatiles from spices: comparison with simultaneous distillation-extraction.
Diaz-Maroto MC, et al.
Journal of Chromatography A, 947(1), 23-29 (2002)
(+)-And (-)-borneol: efficacious positive modulators of GABA action at human recombinant a 1 ? 2 ? 2L GABA A receptors.
Granger RE, et al.
Biochemical Pharmacology, 69(7), 1101-1111 (2005)
Jianyu Su et al.
Journal of food science, 77(6), C658-C664 (2012-05-16)
The aims of this study were to optimize the preparation conditions of natural borneol/β-cyclodextrin (NB/β-CD) inclusion complex by ultrasound method, and to investigate its improvement of stability and solubility. The complex was characterized by different various spectroscopic techniques including Fourier
Xiao-Hong Wei et al.
Microcirculation (New York, N.Y. : 1994), 20(1), 17-29 (2012-08-24)
The present study was designed to evaluate whether CP was beneficial in alleviating myocardial fibrosis following I/R injury. Sprague-Dawley rats were subjected to 30 minutes occlusion of the LADCA, followed by reperfusion. CP (0.4 or 0.8 g/kg) was daily administered starting from
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