68856
Simulated Intestinal Fluid without Enzyme
Dissolution Media Concentrate, Dilute to 25L to conform to USP & EP
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UNSPSC Code:
12164500
Recommended Products
form
liquid
quality
Dilute to 25L to conform to USP & EP
shelf life
limited shelf life, expiry date on the label
pH
6.50-6.60 (25 °C, after dilution)
application(s)
clinical
clinical testing
general analytical
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Application
Dissolution Media Concentrates have been formulated to allow quick and easy dilution to a working solution. The label on each bottle indicates the volume of concentrate in the bottle and the volume to which it must be diluted to provide a final media solution that meets the applicable pharmacopoeia specifications. The user friendly format is designed so that each bottle is a single use unit. The instructions below illustrate just how easy it is to prepare the media.
1. Prepare a clean, dry mixing vessel of a suitable size, 6L, 10L or 25L.
2. Add purified water to approximately one third of the required volume i.e. 2L, 3L or 8L.
3. Carefully pour the entire contents of the bottle of concentrate into the vessel.
4. Rinse the bottle with purified water and add rinsing′s to the mixing vessel.
5. Add purified water to the required volume.
6. Mix thoroughly.
7. Measure the pH and proceed if within specification.
8. Adjust pH if necessary.
1. Prepare a clean, dry mixing vessel of a suitable size, 6L, 10L or 25L.
2. Add purified water to approximately one third of the required volume i.e. 2L, 3L or 8L.
3. Carefully pour the entire contents of the bottle of concentrate into the vessel.
4. Rinse the bottle with purified water and add rinsing′s to the mixing vessel.
5. Add purified water to the required volume.
6. Mix thoroughly.
7. Measure the pH and proceed if within specification.
8. Adjust pH if necessary.
Preparation Note
Dilution to target volume (25 L) results in ~0.616 g/L Sodium hydroxide, ~6.8 g/L Potassium phosphate monobasic.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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