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Ethyl salicylate

analytical standard

Synonym(s):

Ethyl 2-hydroxybenzoate

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About This Item

Linear Formula:
2-(HO)C6H4CO2C2H5
CAS Number:
118-61-6
Molecular Weight:
166.17
Beilstein:
907659
EC Number:
204-265-5
MDL number:
MFCD00002215
UNSPSC Code:
85151701
PubChem Substance ID:
329760515
NACRES:
NA.24

grade

analytical standard

Quality Level

100

vapor pressure

0.05 mmHg ( 25 °C)

Assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

refractive index

n20/D 1.522 (lit.)
n20/D 1.522-1.524

bp

234 °C (lit.)

mp

1 °C (lit.)

density

1.131 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

CCOC(=O)c1ccccc1O

InChI

1S/C9H10O3/c1-2-12-9(11)7-5-3-4-6-8(7)10/h3-6,10H,2H2,1H3

InChI key

GYCKQBWUSACYIF-UHFFFAOYSA-N

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General description

Ethyl salicylate belongs to the class of terpenoids. It is one of the flavor additives typically used in tobacco products. Ethyl salicylate also finds applications as a fragrance ingredient in perfumes, decorative cosmetics, fine fragrances, shampoos, and detergents.

Application

Ethyl salicylate may be used as an analytical standard for the determination of the analyte in biological fluids and topical formulation by chromatography-based techniques.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

212.0 °F - closed cup

Flash Point(C)

100 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC5068
BCCB5123
BCBV0784
BCBP8317V

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Wound healing activity of aqueous extracts of leaves and roots of Coleus aromaticus in rats
Jain AK<, et al.
Acta Poloniae Pharmaceutica, 69, 1119-1123 (2012)
Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation
Pauwels J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 60(1), 51-58 (2012)
Fragrance material review on ethyl salicylate
Lapczynski A, et al.
Food And Chemical Toxicology, 45(1), S397-S401 (2007)
Quantitation of ten flavor compounds in unburned tobacco products.
Lisko JG, et al.
Analytical Methods : Advancing Methods and Applications, 6(13), 4698-4704 (2014)
T Kakkar et al.
Journal of chromatography. B, Biomedical sciences and applications, 718(1), 69-75 (1998-12-01)
A gas chromatographic-mass spectrometric (GC-MS) assay was developed for the quantitative analysis of methyl salicylate (MeS), ethyl salicylate (ES) and salicylic acid (SA) from biological fluids. The method was validated from 100-microl rat liver homogenate preparations (5 mg/ml protein) in

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