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Merck
CN

68082

2,4′-Dibromoacetophenone

derivatization grade (HPLC), LiChropur™, ≥99.0% (HPLC)

Synonym(s):

4′-Bromophenacyl bromide

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About This Item

Linear Formula:
BrC6H4COCH2Br
CAS Number:
99-73-0
Molecular Weight:
277.94
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
329760736
EC Number:
202-783-6
Beilstein/REAXYS Number:
607604
MDL number:
MFCD00000200

Key Documents

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Product Name

2,4′-Dibromoacetophenone, derivatization grade (HPLC), LiChropur™, ≥99.0% (HPLC)

InChI key

FKJSFKCZZIXQIP-UHFFFAOYSA-N

InChI

1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

SMILES string

BrCC(=O)c1ccc(Br)cc1

grade

derivatization grade (HPLC)

assay

≥99.0% (HPLC)

form

solid

quality

LiChropur™

technique(s)

HPLC: suitable

mp

108-110 °C (lit.)
108-112 °C

Quality Level

100

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Related Categories

Application

Derivatisation reagent for HPLC separation of free fatty acids (FFAs) in human plasma, for liquid chromatography-UV-tandem mass spectrometric analysis of perfluorinated carboxylic acids.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCN7813
BCCK6892
BCCJ9295
BCCH8326
BCCF6001

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Jinxue Qiu et al.
Journal of chromatography. A, 1235, 132-140 (2012-03-10)
The presence of perfluorocarboxylates (PFCAs) in the environment is of increasing concern due to their possible toxicity to humans and bioaccumulation in organisms. PFCAs are frequently found in river water, sediment and organisms and sometimes even in groundwater. In order
A Mehta et al.
Journal of chromatography. B, Biomedical sciences and applications, 719(1-2), 9-23 (1998-12-30)
We report a rapid and sensitive method for separation and quantitation of free fatty acids (FFAs) in human plasma using high-performance liquid chromatography (HPLC). Two established techniques of lipid extraction were investigated and modified to achieve maximal FFA recovery in
Wen-Hsin Liu et al.
Toxicology letters, 185(2), 102-109 (2009-01-03)
In view of the controversial role of catalytic activity on the cytotoxicity of phospholipase A(2) (PLA(2)), the present study is conducted to explore whether PLA(2) induces apoptotic process of human leukemia U937 cells through catalytic activity-independent pathway. Modification of His-48
Angelo J Magro et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 12), 1670-1677 (2005-11-23)
The crystal structure of an acidic phospholipase A(2) isolated from Bothrops jararacussu venom (BthA-I) chemically modified with p-bromophenacyl bromide (BPB) has been determined at 1.85 Angstroms resolution. The catalytic, platelet-aggregation inhibition, anticoagulant and hypotensive activities of BthA-I are abolished by
Sanjaya Kuruppu et al.
The Journal of pharmacology and experimental therapeutics, 315(3), 1196-1202 (2005-09-02)
The Papuan taipan (Oxyuranus scutellatus canni) is widely distributed throughout much of Papua New Guinea. Although neurotoxicity is a major symptom of envenomation, no neurotoxins have been isolated from this venom. Using a series of size exclusion chromatography steps, we
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