67862
Homogentisic acid
analytical standard
Synonym(s):
2,5-Dihydroxyphenylacetic acid
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About This Item
Linear Formula:
(HO)2C6H3CH2CO2H
CAS Number:
Molecular Weight:
168.15
EC Number:
207-192-7
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
2692860
Product Name
Homogentisic acid, analytical standard
InChI key
IGMNYECMUMZDDF-UHFFFAOYSA-N
InChI
1S/C8H8O4/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
SMILES string
OC(=O)Cc1cc(O)ccc1O
grade
analytical standard
assay
≥98.0% (GC)
shelf life
limited shelf life, expiry date on the label
mp
150-152 °C (lit.)
application(s)
clinical testing
format
neat
storage temp.
2-8°C
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Application
Homogentisic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
It may also be used as an internal standard for the determination of ascorbic acid (AA) and uric acid (UA) in human plasma samples using high-pressure liquid chromatography–electrochemical detection (HPLC–ECD).
- Urine matrices using reversed-phase liquid chromatography tandem mass spectrometry (LC-MS/MS).
- Strawberry tree honey samples using reversed phase-high performance liquid chromatography (RP-HPLC) and ion chromatography (IC).
It may also be used as an internal standard for the determination of ascorbic acid (AA) and uric acid (UA) in human plasma samples using high-pressure liquid chromatography–electrochemical detection (HPLC–ECD).
General description
Homogentisic acid is a marker of the botanic origin of strawberry tree honey.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Fast HPLC?ECD analysis of ascorbic acid, dehydroascorbic acid and uric acid
Li X, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(10), 853-856 (2009)
Direct chromatographic methods for the rapid determination of homogentisic acid in strawberry tree (Arbutus unedo L.) honey
Scanu R, et al.
Journal of Chromatography A, 1090(1-2), 76-80 (2005)
Urine homogentisic acid and tyrosine: simultaneous analysis by liquid chromatography tandem mass spectrometry
Hughes TA, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 963, 106-112 (2014)
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