Skip to Content
Merck
CN
All Photos(1)

Documents

67653

Supelco

L-Kynurenine

analytical standard

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
β-Anthraniloyl-L-alanine, L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
Empirical Formula (Hill Notation):
C10H12N2O3
CAS Number:
2922-83-0
Molecular Weight:
208.21
MDL number:
MFCD00069912
UNSPSC Code:
41116107

grade

analytical standard

Assay

≥98% (HPLC)

optical activity

[α]25/D -32.5 to -28.0°, c = 0.4 in H2O

shelf life

limited shelf life, expiry date on the label

impurities

≤5.0% water

application(s)

clinical testing

format

neat

SMILES string

N[C@@H](CC(=O)c1ccccc1N)C(O)=O

InChI

1S/C10H12N2O3/c11-7-4-2-1-3-6(7)9(13)5-8(12)10(14)15/h1-4,8H,5,11-12H2,(H,14,15)/t8-/m0/s1

InChI key

YGPSJZOEDVAXAB-QMMMGPOBSA-N

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Key intermediate in the breakdown pathway of tryptophan.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Xue Jiang et al.
International journal of immunopathology and pharmacology, 34, 2058738420950584-2058738420950584 (2020-09-24)
Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360
Ahmed Sadik et al.
Cell, 182(5), 1252-1270 (2020-08-21)
Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor malignancy and suppresses anti-tumor immunity. The context specificity of AHR target genes has so far impeded systematic investigation of AHR activity and its upstream enzymes across human cancers. A

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service