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Sigma-Aldrich

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride

suitable for fluorescence, BioReagent, ≥97.0% (HPLC)

Synonym(s):

1,2-Diamino-4,5-methylenedioxybenzene dihydrochloride, 1,3-Benzodioxole-5,6-diamine dihydrochloride, 5,6-Diamino-1,3-benzodioxole dihydrochloride, MDB

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About This Item

Empirical Formula (Hill Notation):
C7H8N2O2 · 2HCl
CAS Number:
Molecular Weight:
225.07
Beilstein:
5641607
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.32

product line

BioReagent

Quality Level

Assay

≥97.0% (HPLC)

form

solid

fluorescence

λex 367 nm; λem 445 nm in 0.1 M phosphate pH 7.0 (after derivatization with pyruvate)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

Cl[H].Cl[H].Nc1cc2OCOc2cc1N

InChI

1S/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H

InChI key

YXEJRYIEFFUUID-UHFFFAOYSA-N

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General description

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is a fluorescence tag for ⍺-keto acids. It is also required for the derivatization of sialic acids in presence of dilute sulfuric acid. The method allows determination of sialic acids.

Application

Fluorogenic reagent for α-ketoacids.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

may discolor on storage

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S Hara et al.
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Brain and behavior, 5(7), e00334-e00334 (2015-07-30)
Deep brain gray matter (GM) structures are involved in several neurodegenerative disorders and are affected by aging. In this study, we investigated the potential relationship between levels of brain-derived neurotrophic factor (BDNF), a putative biomarker of age- and clinically relevant

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