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63200

Sigma-Aldrich

Maleic anhydride

puriss., ≥99.0% (NT)

Synonym(s):

2,5-Furandione

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About This Item

Empirical Formula (Hill Notation):
C4H2O3
CAS Number:
108-31-6
Molecular Weight:
98.06
Beilstein:
106909
EC Number:
203-571-6
MDL number:
MFCD00005518
UNSPSC Code:
12162002
PubChem Substance ID:
329759813
NACRES:
NA.23

vapor density

3.4 (vs air)

Quality Level

200

vapor pressure

0.16 mmHg ( 20 °C)

grade

puriss.

Assay

≥99.0% (NT)

form

flakes
powder or crystals

autoignition temp.

870 °F

expl. lim.

7.1 %

bp

200 °C (lit.)

mp

51-56 °C (lit.)
52-54 °C

SMILES string

O=C1OC(=O)C=C1

InChI

1S/C4H2O3/c5-3-1-2-4(6)7-3/h1-2H

InChI key

FPYJFEHAWHCUMM-UHFFFAOYSA-N

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General description

Maleic anhydride is a dehydration product of maleic acid that is of considerable industrial importance.

Application

Maleic anhydride has been used as a reference standard for the determination of the analyte in:
  • Workplace air samples by capillary gas chromatography combined with electron capture detection (GC-ECD).

It may be used as a derivatization agent for fatty alcohol ethoxylates in:
  • Industrial mixtures, cleaning products and river and sea waters by high performance liquid chromatography (HPLC) coupled with ultraviolet-visible (UV-Vis) diode array detection (DAD).

Other Notes

For the complete dissociation of enzymes into soluble subunits; For the reversible blocking of amino groups (lysine reagent); P.J.G. Butler, J.I. Harris, B.S. Hartley, R. Lebermann; For the maleylation of proteins

Signal Word

Danger

Hazard Statements

H302,H314,H317,H334,H372

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1A - STOT RE 1 Inhalation

Target Organs

Respiratory system

Supplementary Hazards

EUH071

WGK

WGK 1

Flash Point(F)

217.4 °F

Flash Point(C)

103 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Maleic Anhydride (2013)
[46] Acylation with dicarboxylic acid anhydrides.
M H Klapper et al.
Methods in enzymology, 25, 531-536 (1972-01-01)
The Biochemical Journal, 103, 78-78 (1967)
Dissociation of protein subunits by maleylation.
C L Sia et al.
Biochemical and biophysical research communications, 31(5), 731-737 (1968-06-10)
Determination of fatty alcohol ethoxylates by derivatisation with maleic anhydride followed by liquid chromatography with UV-vis detection.
Mico-Tormos A, et al.
Journal of Chromatography A, 1180(1-2), 32-41 (2008)
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