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Safety Information

59945

Sigma-Aldrich

Isoxanthopterin

≥97.5% (HPLC)

Synonym(s):

2-Amino-4,7-dihydroxy-1,3,5,8-tetraazanaphthalene, 2-Amino-4,7-dihydroxypteridine, 2-Amino-4,7-pteridinediol

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About This Item

Empirical Formula (Hill Notation):
C6H5N5O2
CAS Number:
529-69-1
Molecular Weight:
179.14
Beilstein:
181594
EC Number:
208-469-5
MDL number:
MFCD00006696
UNSPSC Code:
41106305
PubChem Substance ID:
329758638

Assay

≥97.5% (HPLC)

SMILES string

NC1=NC2=C(N=CC(=O)N2)C(=O)N1

InChI

1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)

InChI key

GLKCOBIIZKYKFN-UHFFFAOYSA-N

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ4303

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Highly sensitive assay for xanthine oxidase activity by high-performance liquid chromatography with fluorescence detection.
T Sasaoka et al.
Journal of chromatography, 424(2), 392-397 (1988-02-26)
S Abadeh et al.
Biochimica et biophysica acta, 1117(1), 25-32 (1992-07-21)
Xanthine oxidase was purified from human milk in yields comparable with those obtained from bovine milk. The freshly purified enzyme appeared homogeneous in gel permeation FPLC and SDS-PAGE, consistent with its being a homodimer with total M(r) 290,000 +/- 6000.
Yuichi Komaki et al.
Pulmonary pharmacology & therapeutics, 18(4), 297-302 (2005-03-22)
Reactive oxygen species have been reported to be involved in the airway inflammatory process of chronic obstructive pulmonary disease (COPD). The aim of this study was to quantify the activity of xanthine oxidase (XO), which generates a potent radical superoxide
Ciarán A Smyth et al.
Journal of biomedical optics, 16(7), 077007-077007 (2011-08-03)
Optical techniques toward the realization of sensitive and selective biosensing platforms have received considerable attention in recent times. Techniques based on interferometry, surface plasmon resonance, and waveguides have all proved popular, while spectroscopy in particular offers much potential. Raman spectroscopy
Burki Rajendar et al.
Bioorganic & medicinal chemistry, 17(1), 351-359 (2008-11-18)
Isoxanthopterin (IX) has two edges with hydrogen bond-forming sites suitable for binding to thymine (T) and cytosine (C). The binding affinity of IX for T or C is stronger than for adenine (A) and guanine (G), whereas the base selectivity
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