59945
Isoxanthopterin
≥97.5% (HPLC)
Synonym(s):
2-Amino-4,7-dihydroxy-1,3,5,8-tetraazanaphthalene, 2-Amino-4,7-dihydroxypteridine, 2-Amino-4,7-pteridinediol
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About This Item
Empirical Formula (Hill Notation):
C6H5N5O2
CAS Number:
Molecular Weight:
179.14
EC Number:
208-469-5
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
181594
MDL number:
InChI key
GLKCOBIIZKYKFN-UHFFFAOYSA-N
InChI
1S/C6H5N5O2/c7-6-10-4-3(5(13)11-6)8-1-2(12)9-4/h1H,(H4,7,9,10,11,12,13)
SMILES string
NC1=NC2=C(N=CC(=O)N2)C(=O)N1
assay
≥97.5% (HPLC)
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Determination of biopterin and other pterins in tissues and body fluids by high-performance liquid chromatography.
J H Woolf et al.
Journal of chromatography, 274, 398-402 (1983-05-13)
Irmgard Ziegler
Pigment cell research, 16(3), 172-182 (2003-05-20)
This review describes pteridine biosynthesis and its relation to the differentiation of neural crest derivatives in zebrafish. During the embryonic development of these fish, neural crest precursor cells segregate into neural elements, ectomesenchymal cells and pigment cells; the latter then
N Blau et al.
Clinica chimica acta; international journal of clinical chemistry, 226(2), 159-169 (1994-05-01)
Prenatal diagnosis of tetrahydrobiopterin (BH4) deficiency was undertaken by evaluating the pterin patterns in amniotic fluid and the specific enzyme activities in fetal or extrafetal tissues. This allowed the prenatal diagnosis in 19 pregnancies at risk. In 8 families with
I Ziegler
Journal of cellular biochemistry, 28(3), 197-206 (1985-01-01)
After iodine oxidation, biopterin, 6-hydroxymethylpterin, and 6-formylpterin were identified in mouse spleen lymphocytes by means of reverse-phase HPLC, Crithidia assay, and oxidative degradation. Concanavalin A activation induces a 30-fold increase in the pteridine amounts; biopterin as well as the sum
T Yamamoto et al.
Journal of chromatography. B, Biomedical applications, 681(2), 395-400 (1996-06-07)
An assay for human plasma xanthine oxidase activity was developed with pterin as the substrate and the separation of product (isoxanthopterin) by high-performance liquid chromatography with a fluorescence detector. The reaction mixture consists of 60 microliters of plasma and 240
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