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Toluidine Red

analytical standard

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Synonym(s):
Pigment Red 3
Empirical Formula (Hill Notation):
C17H13N3O3
CAS Number:
Molecular Weight:
307.30
EC Number:
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥98.0% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

270-272 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

Cc1ccc(\N=N\c2c(O)ccc3ccccc23)c(c1)[N+]([O-])=O

InChI

1S/C17H13N3O3/c1-11-6-8-14(15(10-11)20(22)23)18-19-17-13-5-3-2-4-12(13)7-9-16(17)21/h2-10,21H,1H3/b19-18+

InChI key

ZLFVRXUOSPRRKQ-VHEBQXMUSA-N

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General description

Toluidine Red is a synthetic organic dye belonging to the class of azo dyes, widely used for restoring or providing color to processed food products.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Toluidine Red may be used as a reference dye for the quantification of the analyte in food products using high-performance liquid chromatography with gel permeation chromatography clean-up procedure.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simultaneous determination of fifteen illegal dyes in animal feeds and poultry products by ultra-high-performance liquid chromatography tandem mass spectrometry
Liu R, et al.
Journal of Chromatography A, 879(24), 2416-2422 (2011)
Simultaneous determination of 14 oil-soluble synthetic dyes in chilli products by high performance liquid chromatography with a gel permeation chromatography clean-up procedure
Zhu Y, et al.
Food Chemistry, 145(24), 956-962 (2014)
Ying Jiang et al.
Sexually transmitted diseases, 38(3), 244-245 (2010-09-28)
We retrospectively analyzed the Venereal Disease Research Laboratory test, Treponema pallidum particle agglutination test, and toluidine red unheated serum test (TRUST) in 41 cases of HIV-negative neurosyphilis and 34 non-neurologic syphilitic patient and found that serum-TRUST titers could be the
S A Larsen et al.
Journal of clinical microbiology, 17(2), 341-345 (1983-02-01)
Both the rapid plasma reagin (RPR) 18-mm circle card test and the toluidine red unheated serum test (TRUST) were designed to be more rapid than the Venereal Disease Research Laboratory slide test for the serodiagnosis of syphilis. The RPR card
D L Morgan et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 27(12), 793-800 (1989-12-01)
Treatment of F344 rats and B6C3F1 mice with C.I. Pigment Red 3 in the diet (10, 5.0, 2.5, 1.25, 0.6 or 0.3%) for 14 and 90 days resulted in haematological alterations consistent with haemolytic anaemia. Rats appeared to be more

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