Skip to Content
Merck
CN

55695

3-Hydroxy-3-methylglutaric acid

purum, ≥95.0% (GC)

Synonym(s):

3-Hydroxy-3-methylpentanedioic acid

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

Linear Formula:
HOC(CH3)(CH2CO2H)2
CAS Number:
Molecular Weight:
162.14
EC Number:
207-971-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1769194
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

NPOAOTPXWNWTSH-UHFFFAOYSA-N

InChI

1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)

SMILES string

CC(O)(CC(O)=O)CC(O)=O

grade

purum

assay

≥95.0% (GC)

mp

105-108 °C (lit.), 105-109 °C

Looking for similar products? Visit Product Comparison Guide

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Beatriz Puisac et al.
Journal of inherited metabolic disease, 33(4), 405-410 (2010-06-10)
3-Hydroxy-3-methylglutaric aciduria is a rare human autosomal recessive disorder caused by deficiency of 3-hydroxy-3-methylglutaryl CoA lyase (HL). This mitochondrial enzyme catalyzes the common final step of leucine degradation and ketogenesis. Acute symptoms include vomiting, seizures and lethargy, accompanied by metabolic
A Kamal-Eldin et al.
Phytochemistry, 58(4), 587-590 (2001-09-29)
A straight-chain oligomeric structure composed of five secoisolariciresinoldiglucoside (SDG) residues interconnected by four 3-hydroxy-3-methyl glutaric acid (HMGA) residues (molecular weight ca. 4000 Da) was assigned to the main lignan of flaxseed on the basis of nuclear magnetic resonance spectroscopy (NMR).
C Mir et al.
Journal of inherited metabolic disease, 29(1), 64-70 (2006-04-08)
3-Hydroxy-3-methylglutaric aciduria is a rare autosomal recessive genetic disorder that affects ketogenesis and leucine metabolism. The disease is caused by mutations in the gene coding for 3-hydroxy-3-methylglutaryl-coenzyme A lyase (HL). To date 26 different mutations have been described. A (betaalpha)(8)
Elaine A Porter et al.
Phytochemistry, 81, 90-96 (2012-06-23)
LC-UV-MS/MS analysis of leaf extracts from 146 accessions of 71 species of Rosa revealed that some taxa accumulated flavonol O-glycosides acylated with 3-hydroxy-3-methylglutaric acid, which are relatively uncommon in plants. The structures of two previously unrecorded examples isolated from Rosa
S Funghini et al.
Molecular genetics and metabolism, 73(3), 268-275 (2001-07-20)
3-Hydroxy-3-methylglutaric aciduria is a rare autosomal recessive inborn error of metabolism caused by deficiency of the mitochondrial enzyme 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL). Up to now only a few mutations have been reported in the HMGCL gene. We report the first Italian

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service