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Key Documents

Safety Information

53960

Sigma-Aldrich

Hydroquinone

≥99.0% (HPLC)

Synonym(s):

1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ

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About This Item

Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
Molecular Weight:
110.11
Beilstein:
605970
EC Number:
MDL number:
UNSPSC Code:
12352200

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

Assay

≥99.0% (HPLC)

autoignition temp.

930 °F

bp

285 °C (lit.)

mp

171-173 °C
172-175 °C (lit.)

solubility

H2O: 50 mg/mL, clear

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

329.0 °F - closed cup

Flash Point(C)

165 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Se Eun Byeon et al.
Free radical biology & medicine, 57, 105-118 (2013-01-08)
The hydroxylated benzene metabolite hydroquinone (HQ) is mainly generated from benzene, an important industrial chemical, and is also a common dietary component. Although numerous papers have addressed the potential role of HQ in tumorigenic responses, the immunosuppressive and anti-inflammatory effects
Elizabeth T Makino et al.
Journal of drugs in dermatology : JDD, 11(12), 1478-1482 (2013-02-05)
There are numerous common skin disorders involving hyperpigmentation, including solar lentigines, postinflammatory hyperpigmentation, melasma, freckles, and dyschromia from photoaging. While these conditions are of an aesthetic nature, there is great interest in newer, safer, and more effective treatment modalities. Topical
Félix A Urra et al.
Toxicology and applied pharmacology, 267(3), 218-227 (2013-01-22)
Tumor cells present a known metabolic reprogramming, which makes them more susceptible for a selective cellular death by modifying its mitochondrial bioenergetics. Anticancer action of the antioxidant 9,10-dihydroxy-4,4-dimethyl-5,8-dihydroanthracen-1(4H)-one (HQ) on mouse mammary adenocarcinoma TA3, and its multiresistant variant TA3-MTXR, were
Huan Wang et al.
Analytical biochemistry, 434(1), 123-127 (2012-12-04)
Due to high sensitivity and good selectivity, electrochemical immunosensor is often used to detect tumor markers. Prostate-specific antigen (PSA) is the most validated tumor marker for prostate cancer. In this work, mesoporous silica nanoparticles (MSNs) were used to increase the
Amanda J Reig et al.
Nature chemistry, 4(11), 900-906 (2012-10-24)
De novo proteins provide a unique opportunity to investigate the structure-function relationships of metalloproteins in a minimal, well-defined and controlled scaffold. Here, we describe the rational programming of function in a de novo designed di-iron carboxylate protein from the Due

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