52495
Hexadimethrine bromide
≥94% (AT)
Synonym(s):
1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide, Polybrene
InChI
1S/C10H24N2.C3H6Br2/c1-11(2)9-7-5-6-8-10-12(3)4;4-2-1-3-5/h5-10H2,1-4H3;1-3H2
InChI key
KZKAYEGOIJEWQB-UHFFFAOYSA-N
assay
≥94% (AT)
solubility
H2O: 0.1 g/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
2-8°C
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Application
Facilitates automated sequencing of small peptides. Used to coat glass microfiber sheets for protein blotting.
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J Vandekerckhove et al.
European journal of biochemistry, 152(1), 9-19 (1985-10-01)
A procedure has been developed which allows the immobilization on glass-fiber sheets coated with the polyquaternary amine, Polybrene, of proteins and protein fragments previously separated on sodium-dodecylsulfate-containing polyacrylamide gels. The transfer is carried out essentially as has been used for
Automated amino acid sequence of small peptides utilizing Polybrene.
D G Klapper et al.
Analytical biochemistry, 85(1), 126-131 (1978-03-01)
Kimberly A Brown et al.
Journal of cellular biochemistry, 105(2), 596-611 (2008-08-30)
Transforming growth factor-beta 1 (TGF-beta1) is an important growth inhibitor of epithelial cells and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to tumorigenesis. TGF-beta1 signals through the TGF-beta type I and type II receptors, and
[Chemiluminescence of peritoneal macrophages activated by non-natural polyelectrolytes].
L G Korkina et al.
Doklady Akademii nauk SSSR, 282(1), 206-209 (1985-05-01)
Hua Yang et al.
Investigative ophthalmology & visual science, 51(1), 28-34 (2009-08-08)
Pigment epithelium-derived factor (PEDF) is known to be an angiogenesis suppressor and to have antitumor effects. This study investigates whether constitutive overexpression of PEDF inhibits the growth and hepatic micrometastasis of ocular melanoma. Real-time RT-PCR was used to detect endogenous
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