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Sigma-Aldrich

ProClin™ 300

ProClin™ preservative for use in IVD manufacturing, CMIT/MIT 3%, Method Development Kit, pkg of 3 × 5 mL each (three different lots)

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Synonym(s):
3% solution of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-Methyl-4-isothiazolin-3-one
UNSPSC Code:
12352201
NACRES:
NA.21

Quality Level

300

form

liquid

shelf life

3 yr

contains

Alkyl Carboxylate

composition

CMIT/MIT, 3%

packaging

pkg of 3 × 5 mL each (three different lots)

parameter

operating temperature at <45 °C

matrix

Modified glycol

operating pH range

2.5-8.5

pH

4.1(at 100 g/l)

bp

189 °C/1013 hPa

mp

-40 °C

solubility

water: soluble

density

1.030 g/cm3

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Application

ProClin™ preservatives are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin™ toxicity prevent microorganisms from developing high levels of resistance, making ProClin™ highly efficient even over extended storage periods of your IVD components.

Legal Information

ProClin is a trademark of LANXESS Corp.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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James P Higham et al.
PloS one, 6(7), e22398-e22398 (2011-07-30)
Nutritional status is a critical element of many aspects of animal ecology, but has proven difficult to measure non-invasively in studies of free-ranging animals. Urinary C-peptide of insulin (UCP), a small polypeptide cleaved in an equimolar ratio from proinsulin when

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