Skip to Content
Merck
CN

46908

Sulfisomidin

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide, N1-(2,6-Dimethylpyrimidin-4-yl)sulfanilamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H14N4O2S
CAS Number:
515-64-0
Molecular Weight:
278.33
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329757260
EC Number:
208-204-3
Beilstein/REAXYS Number:
261305
MDL number:
MFCD00010567

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

YZMCKZRAOLZXAZ-UHFFFAOYSA-N

InChI

1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)

SMILES string

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

242-243 °C (lit.)

application(s)

clinical testing

format

neat

Quality Level

200

General description

Chemical structure: sulfonamide

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCF1547
BCBS3734V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S P Boom et al.
The Journal of pharmacy and pharmacology, 45(7), 614-617 (1993-07-01)
To investigate whether dogs are able to excrete acetylated drugs by active transport, the plasma kinetics and renal excretion of the N4-acetyl metabolites of sulphasomidine and sulphadimethoxine were studied in the beagle dog after a rapid intravenous bolus injection. Two
A Melander et al.
Acta medica Scandinavica, 211(5), 361-364 (1982-01-01)
The serum concentrations and clinical effects of sulfaisodimidine given during 12 days were examined in two groups of patients with uncomplicated lower urinary tract infection. Group I (n=12) received the drug in a conventional dosage, 1 g four times daily
O Solberg et al.
Acta pathologica et microbiologica Scandinavica. Section B, Microbiology, 89(4), 267-270 (1981-08-01)
Four strains of Neisseria meningitidis were studied during serial passage. From two strains which originally were sulfonamide resistant, variants developed that had altered susceptibility to sulfonamides. One of the variants became relatively highly sulfonamide-sensitive, the other exhibited merely reduced sulfonamide
H Van Gogh et al.
Research in veterinary science, 48(2), 152-157 (1990-03-01)
The influence of gestation on the pharmacokinetics of four sulphonamides was studied in goats before, during and after pregnancy. Similar doses were given as intravenous boluses of 50 mg kg-1 each. Results were compared with those of non-pregnant goats to
T B Vree et al.
Pharmaceutisch weekblad. Scientific edition, 6(4), 150-156 (1984-08-24)
Sulfisomidine, sulfamethomidine, sulfadimethoxine and their corresponding N4-acetyl derivatives were administered to man. The percentages of acetylation and deacetylation and those of protein binding, the half-lives of elimination and the apparent and true renal clearance values were measured. No acetylation phenotype
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service