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Pyrantel pamoate

VETRANAL®, analytical standard

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Synonym(s):
1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid), Pyrantel embonate
Linear Formula:
C11H14N2S · C23H16O6
CAS Number:
22204-24-6
Molecular Weight:
594.68
Beilstein:
9034755
EC Number:
244-837-1
MDL number:
MFCD00072037
UNSPSC Code:
41116107
PubChem Substance ID:
329756621
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

CN1CCCN=C1\C=C\c2cccs2.OC(=O)c3cc4ccccc4c(Cc5c(O)c(cc6ccccc56)C(O)=O)c3O

InChI

1S/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3/b;6-5+

InChI key

AQXXZDYPVDOQEE-MXDQRGINSA-N

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General description

Chemical structure: tetrahydropyrimidine

Application

Pyrantel pamoate may be used as a reference standard in the determination of pyrantel pamoate in dog plasma and veterinary tablets using high performance liquid chromatography (HPLC) and mid-infrared spectroscopy (IR), respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of fenbendazole, praziquantel and pyrantel pamoate in dog plasma by high-performance liquid chromatography.
Morovjan G, et al.
Journal of Chromatography A, 797(1-2), 237-244 (1998)
Chemometric quality inspection control of pyrantel pamoate, febantel and praziquantel in veterinary tablets by mid infrared spectroscopy.
Piantavini S M, et al.
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 125, 396-403 (2014)
Yutong Chen et al.
International journal of oncology, 55(1), 142-156 (2019-05-23)
Matrix metalloproteinase‑1 (MMP1) participates in the metastasis of pancreatic cancer, and its expression can be regulated by endogenous microRNAs (miRs/miRNAs) and exogenous inflammatory factors. Whether miRNAs that potentially modulate MMP1 expression can also attenuate the pro‑metastatic effects of its inducer
Education and imaging. Gastrointestinal: ascariasis.
A Suzuki et al.
Journal of gastroenterology and hepatology, 23(11), 1770-1770 (2009-01-06)
Vinod K Gupta et al.
Journal of colloid and interface science, 350(1), 330-335 (2010-07-21)
Adsorption and electrochemical reduction of pyrantel pamoate are studied in Britton Robinson buffer medium at hanging mercury drop electrode (HMDE) by Adsorptive Stripping Voltammetric technique. The peak current shows a linear dependence with the drug concentration over the range 250
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