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Safety Information

46424

Supelco

Formothion solution

~80% in xylene, PESTANAL®, analytical standard

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Synonym(s):
S-[2-(Formylmethylamino)-2-oxoethyl] O,O-dimethyl dithiophosphate
Empirical Formula (Hill Notation):
C6H12NO4PS2
CAS Number:
Molecular Weight:
257.27
Beilstein:
5942199
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

contains

acetic acid anhydride as stabilizer

concentration

~80% in xylene

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture

format

neat

storage temp.

2-8°C

SMILES string

[H]C(=O)N(C)C(=O)CSP(=S)(OC)OC

InChI

1S/C6H12NO4PS2/c1-7(5-8)6(9)4-14-12(13,10-2)11-3/h5H,4H2,1-3H3

InChI key

AIKKULXCBHRFOS-UHFFFAOYSA-N

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General description

Formothion is classified under the group of organophosphorus (OP) insecticides utilized for the protection of crops from a variety of sucking pests and some biting and chewing insects. Its mode of action involves the inhibition of cholinesterase enzyme and it is a suspected endocrine disruptor.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Target Organs

Central nervous system,Liver,Kidney, Respiratory system

WGK

WGK 3

Flash Point(F)

77.0 °F

Flash Point(C)

25 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

易制毒化学品(2类)
危险化学品

Certificates of Analysis (COA)

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Residue Reviews, 77 (2012)
K Sancewicz-Pach et al.
Przeglad lekarski, 54(10), 741-744 (1997-01-01)
44 pregnant women were treated at the Department of Clinical Toxicology in years 1986-1996 as a result of acute poisonings with different xenobiotics. Acute pesticide poisoning that involved 4 cases were always severe and had dramatic clinical course. Carbofuran intoxication
M D Awal et al.
Veterinary and human toxicology, 36(3), 199-202 (1994-06-01)
The effect of long-term exposure to the organophosphate insecticide Anthio on serum esterases and ruminal microorganisms of male calves was investigated. The daily oral administration of 3, 6 or 12 mg Anthio/kg/d for 90 d caused significant inhibition of serum
The Pesticide Encyclopedia (2014)
N K Shamsieva et al.
Problemy endokrinologii, 39(2), 49-51 (1993-03-01)
Under study were activities of glycolysis enzymes: LDH, Krebs' cycle--SDH, those of electron transport system--NAD and NADP-diaphorase, and of the hydrolytic enzymes, acid and alkaline phosphatases in the hypothalamus, as were morphofunctional shifts in these enzymes' activities in poisoning with

Protocols

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