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Supelco

Furazolidone

VETRANAL®, analytical standard

Synonym(s):

3-(5-Nitrofurfurylideneamino)-2-oxazolidinone

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About This Item

Empirical Formula (Hill Notation):
C8H7N3O5
CAS Number:
67-45-8
Molecular Weight:
225.16
Beilstein:
8317414
EC Number:
200-653-3
MDL number:
MFCD00010550
UNSPSC Code:
41116107
PubChem Substance ID:
329757127
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

antibiotic activity spectrum

Gram-positive bacteria
parasites

application(s)

cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

format

neat

Mode of action

enzyme | inhibits

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CCOC2=O)o1

InChI

1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2/b9-5+

InChI key

PLHJDBGFXBMTGZ-WEVVVXLNSA-N

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General description

Furazolidone is an effective antiprotozoal and antibacterial agent.

Application

Furazolidone may be used as a reference standard:
  • For the determination of the analyte in pharmaceutical formulations by second-derivative spectrophotometry.
  • For the determination of the analyte in animal feeds using liquid chromatography with ultraviolet and thermospray mass spectrometric detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361fd

Hazard Classifications

Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB8037

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Formulation and advantages of furazolidone in liposomal drug delivery systems.
Alam MI, et al.
European Journal of Pharmaceutical Sciences, 84, 139- 145 (2016)
Determination of furazolidone in animal feeds using liquid chromatography with UV and thermospray mass spectrometric detection.
McCracken RJ and Kennedy DG
Journal of Chromatography A, 771(1-2), 349- 354 (1997)
C V Prasad et al.
Journal of pharmaceutical and biomedical analysis, 21(5), 961-968 (2000-03-07)
A second-derivative spectrophotometric procedure has been developed for the simultaneous determination of tinidazole (TD), furazolidone (FD) and diloxanide furoate (DF) in a commercial preparation. The method consists of the utilization of second-derivative absorption spectra of tablet extract in distilled water
Pharmacology and toxicity of furazolidone in man and animals: some recent research.
B H Ali
General pharmacology, 20(5), 557-563 (1989-01-01)
Hafez Fakheri et al.
Helicobacter, 17(1), 43-48 (2012-01-10)
Sequential regimens have been recently reported to be superior to the standard triple therapies in Helicobacter pylori eradication, but most of these studies were performed in Europe and data from developing countries are lacking. So we designed a study to
View All Related Papers

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