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46190

Supelco

Dienestrol

VETRANAL®, analytical standard

Synonym(s):

3,4-Bis(4-hydroxyphenyl)-2,4-hexadiene

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About This Item

Empirical Formula (Hill Notation):
C18H18O2
CAS Number:
84-17-3
Molecular Weight:
266.33
Beilstein:
2053694
EC Number:
201-519-7
MDL number:
MFCD00050983
UNSPSC Code:
41116107
PubChem Substance ID:
329757096
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C\C=C(c1ccc(O)cc1)\C(=C\C)c2ccc(O)cc2

InChI

1S/C18H18O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h3-12,19-20H,1-2H3/b17-3+,18-4+

InChI key

NFDFQCUYFHCNBW-SCGPFSFSSA-N

Gene Information

human ... ESR1(2099)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H350,H361d

Hazard Classifications

Carc. 1B - Repr. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCB2746
BCBZ4033
BCBS5824V

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T Oda et al.
Biological & pharmaceutical bulletin, 18(10), 1435-1438 (1995-10-01)
We have previously reported the inhibitory effects of diethylstilbestrol (1) and optically active indenestrol derivatives on microtubule polymerization in vitro and their disruptive effect on cytoplasmic microtubules and cytotoxicity in cultured Chinese hamster V79 cells. In the present study, the
Muhammad Saeed et al.
Steroids, 70(3), 173-178 (2005-03-15)
A method for the synthesis of 2-hydroxyestrone/estradiol, 4-hydroxyestrone/estradiol, 3'-hydroxydiethylstilbestrol, 3'-hydroxyhexestrol, and 3'-hydroxydienestrol is reported, in which 2-iodoxybenzoic acid (IBX) and the corresponding phenolic estrogen are reacted. Treatment of the natural estrogens, estrone/estradiol, with stoichiometric amounts of IBX in dimethylformamide initially
S K Banerjee et al.
Mutation research, 311(2), 191-197 (1994-12-01)
Estrogens, both natural and synthetic, have been implicated in carcinogenesis at different organ sites in a variety of animals, including man, for more than six decades. However, the molecular mechanism(s) involved in the carcinogenic action of estrogens still remains both
M Bygdeman et al.
Maturitas, 23(3), 259-263 (1996-04-01)
This study was designed to evaluate the efficacy of Replens, a non-hormonal moisturizing vaginal gel, on symptoms of vaginal atrophy in postmenopausal women, in comparison with Dienoestrol (Cilag), an oestrogenic vaginal cream. Thirty-nine patients were randomly allocated to either of
D M Ignar-Trowbridge et al.
Endocrinology, 129(5), 2423-2430 (1991-11-11)
The effect of estrogen on phosphoinositide (PI) metabolism was evaluated in the immature mouse uterus, a tissue which undergoes estrogen-induced proliferation. Uteri isolated from untreated mice or from mice injected ip with diethylstilbestrol (DES) were incubated with [3H]myo-inositol and assessed
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