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46036

Supelco

Brodifacoum

PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C31H23BrO3
CAS Number:
56073-10-0
Molecular Weight:
523.42
Beilstein:
8171403
EC Number:
259-980-5
MDL number:
MFCD00084803
UNSPSC Code:
41116107
PubChem Substance ID:
329757068
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

OC1=C(C2CC(Cc3ccccc23)c4ccc(cc4)-c5ccc(Br)cc5)C(=O)Oc6ccccc16

InChI

1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

InChI key

VEUZZDOCACZPRY-UHFFFAOYSA-N

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General description

Brodifacoum is an anticoagulant rodenticide, widely used for the control of rodent population via inhibition of the vitamin K epoxide reductase, causing blood clotting alterations, leading to haemorrhaging as the ultimate cause of death.

Application

Brodifacoum may be used as an analytical reference standard for the quantification of the analyte in animal samples and biological samples using different chromatography techniques..
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A - STOT RE 1

Target Organs

Blood

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF1546
BCBS3140V
BCBR9161V
SZBC214XV
SZB8324XV

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. For what applications can Product 46036, Brodifacoum, be used?

    This product consists of a coumarin analog. It has anticoagulant activity and has been described as a rodenticide.

  6. What is the purity of Product 46036, Brodifacoum?

    This product does not have a purity specification. However, the purity is provided on the certificate of analysis of each lot.

  7. What is Product 46036, Brodifacoum, soluble in?

    This product is insoluble in water. It is slightly soluble in alcohol and benzene. It is soluble in acetone and chloroform.

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

The determination of the anticoagulant rodenticide brodifacoum in blood serum by liquid chromatography with fluorescence detection
Felice.JL and Murphy.JM
Journal of Analytical Toxicology, 13(4), 229-231 (1989)
So Young Kim et al.
Annals of clinical and laboratory science, 40(3), 300-303 (2010-08-07)
We report a case of brodifacoum (superwarfarin) intoxication of unknown etiology presenting as hemoperitoneum after fluconazole administration for one week before the onset of symptoms. The initial prothrombin time (PT) and partial thromboplastin time (PTT) were markedly prolonged, although a
Jason Reese et al.
Clinical nephrology, 78(4), 312-315 (2012-09-18)
A 59-year-old woman was admitted to the internal medicine service after presenting to the emergency department with complaints of abdominal pain and hematuria. Upon further evaluation, the patient was found to be significantly coagulopathic secondary to the intentional ingestion of
Reversed-phase HPLC determination of eight anticoagulant rodenticides in animal liver
Fauconnet.V, et al.
Journal of Analytical Toxicology, 21(7), 548-553 (1997)
Servet Altay et al.
Cardiovascular journal of Africa, 23(9), e9-e11 (2012-10-31)
Superwarfarins (brodifacoum, difenacoum, bromodialone and chlorphacinone) are anticoagulant rodenticides that were developed in 1970s to overcome resistance to warfarin in rats. A 26-year-old previously healthy man was admitted to the emergency department with epigastric pain, severe upper and lower gastrointestinal
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