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Merck
CN

45622

Phosphamidon

PESTANAL®, analytical standard

Synonym(s):

2-Chloro-N,N-diethyl-3-(dimethylphosphono)crotonic amide

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About This Item

Empirical Formula (Hill Notation):
C10H19ClNO5P
CAS Number:
Molecular Weight:
299.69
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
236-116-5
Beilstein/REAXYS Number:
8323501
MDL number:
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Product Name

Phosphamidon, PESTANAL®, analytical standard

InChI

1S/C10H19ClNO5P/c1-6-12(7-2)10(13)9(11)8(3)17-18(14,15-4)16-5/h6-7H2,1-5H3/b9-8+

InChI key

RGCLLPNLLBQHPF-CMDGGOBGSA-N

SMILES string

CCN(CC)C(=O)\C(Cl)=C(\C)OP(=O)(OC)OC

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

Quality Level

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Application

Phosphamidon may be used as a reference standard in the analysis of phosphamidon in tobacco samples using gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Phosphamidon is a neurotoxic organophosphorus insecticide.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品
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Male reproductive toxicity of phosphamidon: histopathological changes in epididymis.
Akbarsha MA and P Sivasamy
Indian Journal of Experimental Biology, 36(1), 34-38 (1998)
Comparative study of pesticide multi-residue extraction in tobacco for gas chromatography-triple quadrupole mass spectrometry.
Lee M-J, et al.
Journal of Chromatography A, 1187(1-2), 25-33 (2008)
S G Suke et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 41(9), 765-768 (2008-09-30)
The effect of N-acetylcysteine, a thiolic antioxidant, on attenuation of phosphamidon-induced oxidative stress and immune dysfunction was evaluated in adult male Wistar rats weighing 200-250 g. Rats were divided into four groups, 8 animals/group, and treated with phosphamidon, N-acetylcysteine or
Sandhya Rabindranathan et al.
Journal of hazardous materials, 102(2-3), 217-229 (2003-09-16)
The photocatalytic degradation of a small concentration of an organo-phosphorous (OP) insecticide phosphamidon, in water, on ZnO and TiO(2) is investigated. Of the two semiconductor oxides, TiO(2) is found to be more effective as a photocatalyst for this reaction. Several
J G Zhuang et al.
The Annals of occupational hygiene, 37(1), 89-99 (1993-02-01)
This paper describes the approach of setting an occupational exposure limit for phosphamidon, an organophosphorus pesticide, in the workplace in China. Apart from a general review of the literature relating to various toxicological studies, special emphasis has been placed on

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