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Merck
CN

45622

Phosphamidon

PESTANAL®, analytical standard

Synonym(s):

2-Chloro-N,N-diethyl-3-(dimethylphosphono)crotonic amide

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About This Item

Empirical Formula (Hill Notation):
C10H19ClNO5P
CAS Number:
13171-21-6
Molecular Weight:
299.69
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329756838
EC Number:
236-116-5
Beilstein/REAXYS Number:
8323501
MDL number:
MFCD00055301

Key Documents

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InChI

1S/C10H19ClNO5P/c1-6-12(7-2)10(13)9(11)8(3)17-18(14,15-4)16-5/h6-7H2,1-5H3/b9-8+

InChI key

RGCLLPNLLBQHPF-CMDGGOBGSA-N

SMILES string

CCN(CC)C(=O)\C(Cl)=C(\C)OP(=O)(OC)OC

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

Quality Level

100

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General description

Phosphamidon is a neurotoxic organophosphorus insecticide.

Application

Phosphamidon may be used as a reference standard in the analysis of phosphamidon in tobacco samples using gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品
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Certificates of Analysis (COA)

Lot/Batch Number
BCCM6122
BCCG8204
BCCB4841
BCBV8236
BCBT7188

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Comparative study of pesticide multi-residue extraction in tobacco for gas chromatography-triple quadrupole mass spectrometry.
Lee M-J, et al.
Journal of Chromatography A, 1187(1-2), 25-33 (2008)
J G Zhuang et al.
The Annals of occupational hygiene, 37(1), 89-99 (1993-02-01)
This paper describes the approach of setting an occupational exposure limit for phosphamidon, an organophosphorus pesticide, in the workplace in China. Apart from a general review of the literature relating to various toxicological studies, special emphasis has been placed on
Angela Rouvalis et al.
Ecotoxicology and environmental safety, 72(3), 828-833 (2008-11-11)
Rainwater samples from four municipalities located in Achaia Prefecture, Greece, were collected from March to September 2006. The toxic potency of pollutants present in 36 rainwater samples was tested using Daphnia pulex. The pesticide determination was conducted with GC-MS. Only
Male reproductive toxicity of phosphamidon: histopathological changes in epididymis.
Akbarsha MA and P Sivasamy
Indian Journal of Experimental Biology, 36(1), 34-38 (1998)
S G Suke et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 41(9), 765-768 (2008-09-30)
The effect of N-acetylcysteine, a thiolic antioxidant, on attenuation of phosphamidon-induced oxidative stress and immune dysfunction was evaluated in adult male Wistar rats weighing 200-250 g. Rats were divided into four groups, 8 animals/group, and treated with phosphamidon, N-acetylcysteine or
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