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Key Documents

Safety Information

45340

Sigma-Aldrich

(±)-Epichlorohydrin

purum, ≥99% (GC)

Synonym(s):

(±)-2-(Chloromethyl)oxirane, 1-Chloro-2,3-epoxypropane

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2.5 KG
CN¥1,336.16
5 KG
CN¥1,666.70

CN¥1,336.16


Available to ship onApril 27, 2025Details


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2.5 KG
CN¥1,336.16
5 KG
CN¥1,666.70

About This Item

Empirical Formula (Hill Notation):
C3H5ClO
CAS Number:
Molecular Weight:
92.52
Beilstein:
79785
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

CN¥1,336.16


Available to ship onApril 27, 2025Details


Request a Bulk Order

vapor density

3.2 (vs air)

Quality Level

vapor pressure

13.8 mmHg ( 21.1 °C)

grade

purum

Assay

≥99% (GC)

autoignition temp.

779 °F

expl. lim.

21 %

impurities

≤0.1% water

color

APHA: ≤20

refractive index

n20/D 1.438 (lit.)
n20/D 1.438

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1 of 4

This Item
529600C7594B6429
form

liquid

form

liquid

form

powder blend

form

solution

storage condition

OK to freeze

storage condition

OK to freeze

storage condition

-

storage condition

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

room temp

shipped in

ambient

shipped in

ambient

shipped in

-

shipped in

-

manufacturer/tradename

Novagen®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

-

manufacturer/tradename

-

General description

(±)-Epichlorohydrin is an organochlorine compound, used in the manufacturing of epoxy resins, plasticizers, dye stuffs, lubricants, pharmaceuticals, adhesives and oil emulsification products.[1]

Application


  • Pitfalls in the synthesis of fluorescent methotrexate oligopeptide conjugates.: Addresses challenges in synthesizing fluorescent methotrexate conjugates using Fmoc-Lys(Boc)-OH, aiming to optimize peptide-based drug delivery systems (Sebestyén et al., 2016).

  • Fluoreometric behavior of a novel bis-acridine orange bound to double stranded DNA.: Explores the fluorescent properties of a bis-acridine compound integrated with Fmoc-Lys(Boc)-OH for potential applications in DNA interaction studies (Takenaka et al., 2003).

  • Bis-naphthalene diimide exhibiting an effective bis-threading intercalating ability.: Investigates a bis-naphthalene diimide derivative, facilitated by Fmoc-Lys(Boc)-OH, demonstrating significant DNA intercalation, useful for gene therapy and molecular biology research (Nojima et al., 2003).

  • Novel synthesis of a tetra-acridinyl peptide as a new DNA polyintercalator.: Details the synthesis of a new DNA polyintercalator using Fmoc-Lys(Boc)-OH, highlighting its potential to enhance molecular diagnostics and therapeutic strategies (Ueyama et al., 2000).



Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Repr. 2 - Skin Corr. 1B - Skin Sens. 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

82.4 °F

Flash Point(C)

28 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Synthesis of (R)-and (S)-epichlorohydrin.
Baldwin JJ, et al.
The Journal of Organic Chemistry, 43(25), 4876-4878 (1978)
Clinical Environmental Health and Toxic Exposures (2001)
Study of the crosslinking reaction between epichlorohydrin and starch.
Kuniak L and Marchessault RH.
Starch/Staerke, 24(4), 110-116 (1972)
Preparation and characterization of water soluble high molecular weight ?-cyclodextrin-epichlorohydrin polymers.
Renard E, et al.
European Polymer Journal, 33(1), 49-57 (1997)
Xing Xu et al.
Journal of colloid and interface science, 440, 219-228 (2014-12-03)
Amine-impregnated cotton stalk (AICS) prepared by the reaction of cotton stalk with epichlorohydrin, pyridine and trimethylamine was used as the effective adsorbent for perchlorate removal. Solid-state (13)C NMR spectra, FT-IR, BET principle and element analysis provided evidence that amine groups

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