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45328

Supelco

ANTU

PESTANAL®, analytical standard

Synonym(s):

N-(1-Naphthyl)thiourea

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About This Item

Empirical Formula (Hill Notation):
C11H10N2S
CAS Number:
86-88-4
Molecular Weight:
202.28
Beilstein:
778118
EC Number:
201-706-3
MDL number:
MFCD00041824
UNSPSC Code:
41116107
PubChem Substance ID:
329756649
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

SMILES string

NC(=S)Nc1cccc2ccccc12

InChI

1S/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14)

InChI key

PIVQQUNOTICCSA-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300 - H351

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 2

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
农药列管产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW2054
BCBS1997V
SZBD156XV
SZBA127XV
SZBA127X

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Emine Yilmaz Sipahi et al.
Pharmacological research, 50(6), 585-591 (2004-10-27)
Oxidation of the low-density lipoprotein (LDL) results in the production of modified LDLs. Oxidation of LDL cholesterol plays a role on the pathogenesis of endothelial dysfunction. This study was designed to investigate the possible participation of the oxidative modification of
B P Guery et al.
American journal of respiratory and critical care medicine, 155(5), 1777-1784 (1997-05-01)
Keratinocyte growth factor (KGF) prevents alpha-naphthylthiourea (ANTU)-induced permeability edema ex vivo. To explore the mechanisms in this involved effect, we administered KGF (5 mg/kg, intratracheally) 48 h prior to ANTU (50 mg/kg, intraperitoneally). Several groups were studied: phosphate-buffered saline/dimethylsulfoxide (PBS/DMSO)
J D Tutor et al.
American journal of respiratory and critical care medicine, 149(5), 1107-1111 (1994-05-01)
Tumor necrosis factor (TNF), a compartmentalized cytokine, is a key mediator in the systemic inflammatory response syndrome and may play a role in multiorgan failure. To assess whether compartmentalization of alveolar TNF is preserved following lung injury, isolated perfused lungs
Sharon Rounds et al.
Transactions of the American Clinical and Climatological Association, 119, 155-167 (2008-07-04)
RhoA is an important modulator of endothelial monolayer permeability. Posttranslational carboxyl methylation of small GTPases, such as RhoA and Ras, regulates subcellular localization and GTPase activity, resulting in altered cellular function. In this study, we investigated the role of RhoA
E Sipahi et al.
Pharmacological research, 33(6), 375-378 (1996-06-01)
Alpha-naphthylthiourea when injected intraperitoneally to rats (10 mg kg-1 i.p.) produced lung oedema as indicated by an increase in lung weight/body ratio and pleural effusion reaching a maximum within 4 hours. Prior intravenous single bolus injection of endothelin-1 elicited a
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