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44783

Supelco

Flupirtine

analytical standard

Synonym(s):

Ethyl-N-[2-amino-6-(4-fluorophenylmethylamino) pyridin-3-yl]carbamate

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About This Item

Empirical Formula (Hill Notation):
C15H17FN4O2
CAS Number:
56995-20-1
Molecular Weight:
304.32
Beilstein:
493526
EC Number:
260-503-8
MDL number:
MFCD00864265
UNSPSC Code:
41116107
PubChem Substance ID:
329756545
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

storage temp.

2-8°C

SMILES string

FC1=CC=C(CNC2=NC(N)=C(NC(OCC)=O)C=C2)C=C1

InChI

1S/C15H17FN4O2/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20)

InChI key

JUUFBMODXQKSTD-UHFFFAOYSA-N

General description

Flupirtine belongs to N-methyl-D-aspartate class of drugs. It is a centrally acting non opioid analgesic with muscle relaxant and neuroprotective properties.

Application

Flupirtine may be used as a reference drug for the determination of flupirtine in biological samples by liquid chromatography combined with tandem mass spectrometry (HPLC-MS/MS).

Recommended products

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF4871
BCBW9395
BCBT9364

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Flupirtine Determination in Human Blood Plasma by HPLC with Mass-Spectrometric Detection and its Application to Pharmacokinetic Studies.
Krasnykh L M, et al.
Pharma Chemica, 51(12), 1123-1128 (2018)
Bioanalytical method validation and quantification of flupirtine in canine plasma by HPLC with spectrofluorimetric detection.
De Vito V, et al.
American Journal of Animal and Veterinary Sciences, 10(2), 91-100 (2015)
Antioxidant properties of the triaminopyridine, flupirtine. Biochemical pharmacology
Gassen M, et al.
Biochemical Pharmacology, 56(10), 1323-1329 (1998)

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