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AmberChrom™ 1X8 Ion Exchange Resin

chloride form, 20-50 mesh

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Linear Formula:
(C10H12 · C10H10 · C8H8 · C3H9N)X
CAS Number:
69011-19-4
MDL number:
MFCD00132718
UNSPSC Code:
12000000
NACRES:
SB.52

product name

AmberChrom™ 1X8 chloride form, chloride form, 20-50 mesh

Quality Level

200

description

cross-linkage 8%
strongly basic

form

beads

parameter

66 °C OH- form max. temp.

technique(s)

LPLC: suitable

loss

~50% loss on drying, 110 °C

matrix

styrene-divinylbenzene (gel)

matrix active group

quaternary ammonium

particle size

20-50 mesh

operating pH

0-14

capacity

1.2 meq/mL by wetted bed volume

separation technique

anion exchange

InChI

1S/C10H12.C10H10.C8H8.C3H9N/c2*1-3-9-7-5-6-8-10(9)4-2;1-2-8-6-4-3-5-7-8;1-4(2)3/h3,5-8H,1,4H2,2H3;3-8H,1-2H2;2-7H,1H2;1-3H3

InChI key

HADXLRSCRPYPJJ-UHFFFAOYSA-N

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General description

"p.a." grade resins have been cleaned to remove residual metals, and are purified for analytical use.
Dowex 1X8 is a strongly basic anion exchange resin which is used as an absorbent in solid phase extraction.

Application

Dowex 1X8 chloride form was used:
  • to separate the 3H2O from D[2-3H] glucose using Dowex columns
  • in a assay to determine the pantothenate kinase using Dowex column
  • to separate inositol phosphates (IPs) from myo-[3H]inositol by Dowex chromatography
Strongly basic (type I) anion exchange resin for fine chemical processing; meets requirements of FDA Food Additive Regulation 21 CFR 173.25.

Warning

may contain black particles

Legal Information

Amberchrom is a trademark of DuPont de Nemours, Inc.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How can a Dowex type 1 resin in the chloride form be converted to the carbonate form?

    As one might expect, the procedure requires the use of sodium carbonate (Na2CO3).Citation: Journal of Experimental Medicine, 120, 1007-1018 (1965).From page 1011 of that paper:"A 2 mL column of washed Dowex-1X8 200 to 400 mesh, in the chloride form, was converted to the carbonate form by washing with 1 M Na2CO3 until no chloride could be detected in the eluate. It was then washed with distilled water until the pH of the eluate reached neutrality". The simplest test for chloride is to use a dilute silver nitrate solution. If mixing a few drops of the eluate with a few drops of a silver nitrate solution results in a silver chloride precipitate forming, that would an indication that the eluate contains chloride. You could also use a chloride-specific electrode, if you have access to one.

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L M King et al.
Cardiovascular research, 39(2), 381-392 (1998-11-03)
Experimental data from isolated rat hearts suggest that glycolysis in severe myocardial ischemia is inhibited by accumulation of glycolytic metabolites. In contrast, positron emission tomography (PET) in patients with myocardial ischemia records a 'mismatch' between the decreased coronary flow in
M N Fisher et al.
FEBS letters, 190(2), 293-296 (1985-10-14)
The relative tissue activities of pantothenate kinase range from 1 to 5 nmol . min-1 . g-1 wet wt for heart, brain, kidney, and liver. The enzyme partially purified from each tissue is inhibited by CoA, but there is a
A Cedazo-Mínguez et al.
FEBS letters, 504(1-2), 45-49 (2001-08-28)
The mechanism(s) by which the E4 isoform of apolipoprotein E (apoE4) influences Alzheimer's disease (AD) are not fully known. We report that apoE4, but not apoE3, disrupts carbachol-stimulated phosphoinositide (PI) hydrolysis in SH-SY5Y neuroblastoma cells. Carbachol responses were also disrupted
Ayşem Uzer et al.
Forensic science international, 174(2-3), 239-243 (2007-06-09)
The Meisenheimer anions formed from TNT in KOH solutions in alcohol or acetone were used in screening tests for TNT among possible nitro-explosives. The same reaction was used for the spectrophotometric assay of TNT in soil by CRREL (Cold Regions

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