Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

439142

Supelco

Chloroform

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
Methylidyne trichloride, Trichloromethane
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
67-66-3
Molecular Weight:
119.38
Beilstein:
1731042
MDL number:
MFCD00000826
UNSPSC Code:
12190000
PubChem Substance ID:
24867327

vapor density

4.1 (vs air)

Quality Level

100

vapor pressure

160 mmHg ( 20 °C)

Assay

≥99.8%

form

liquid

contains

0.5-1.0% ethanol as stabilizer

packaging

PVC-coated bottle of 4, 4x4 L

technique(s)

HPLC: suitable

impurities

<0.01% water

evapn. residue

<0.0003%

color

APHA: ≤10

refractive index

n20/D 1.445 (lit.)

bp

60.5-61.5 °C (lit.)

mp

−63 °C (lit.)

density

1.48 g/mL at 25 °C
1.492 g/mL at 25 °C (lit.)

cation traces

Pb: ≤0.05 ppm

λ

H2O reference

UV absorption

λ: 245 nm Amax: 1.00
λ: 255 nm Amax: 0.15
λ: 260 nm Amax: 0.15
λ: 270 nm Amax: 0.02
λ: 290-400 nm Amax: 0.01

application(s)

food and beverages

SMILES string

ClC(Cl)Cl

InChI

1S/CHCl3/c2-1(3)4/h1H

InChI key

HEDRZPFGACZZDS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Chloroform is a colorless, volatile chlorinated organic solvent whose vapors have a narcotic effect. It is susceptible to degradation with time, which can be suppressed by adding ethanol as a stabilizer. Since ethanol is added in higher concentration it leads to increase in polarity which may have a potential influence on some of the applications. Reports suggest that chloroform stabilized with ethanol reduces chances on creating artifacts during the chromatographic separation after extraction of anthracyclines from biological matrices.

Application

Chloroform was used as an organic phase in the methylene blue (MB) two-phase titration process for estimating the cationic surfactant content in high salinity brine.
It may be used as:
  • Solvent for electropolymerization.
  • Solvent for recrystallization.
  • Extractant in solvent extraction process.

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Leyu Cui et al.
Analytical chemistry, 86(22), 11055-11061 (2014-11-05)
The methylene blue (MB) two-phase titration method is a rapid and efficient method for determining the concentrations of anionic surfactants. The point at which the aqueous and chloroform phases appear equally blue is called Epton's end point. However, many inorganic
Solubility controlled electropolymerisation and study of the impact of regioregularity on the spectroelectrochemical properties of thin films of poly (3-octylthiophenes).
Jarosz T, et al.
Electrochimica Acta, 122, 66-71 (2014)
Eagleson M.
Concise Encyclopedia Chemistry, 216-216 (1994)
Traces of phosgene in chloroform: Consequences for extraction of anthracyclines.
Maudens KE, et al.
Journal of Chromatography. B, Biomedical Applications, 848(2), 384-390 (2007)
Electrogenerated chemiluminescent emission from an organized (L-B) monolayer of a Ru(bpy)32+-based surfactant on semiconductor and metal electrodes.
Zhang X and Bard AJ.
The Journal of Physical Chemistry, 92(20), 5566-5569 (1988)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service