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Key Documents

Safety Information

437549

Sigma-Aldrich

Ethyl acetate

ACS reagent, ≥99.5%

Synonym(s):

EtOAc

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500 ML
CN¥647.86
2.5 L
CN¥2,323.82

CN¥647.86


Estimated to ship onJune 27, 2025Details


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500 ML
CN¥647.86
2.5 L
CN¥2,323.82

About This Item

Linear Formula:
CH3COOC2H5
CAS Number:
Molecular Weight:
88.11
Beilstein:
506104
EC Number:
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:

grade:
ACS reagent
bp:
76.5-77.5 °C (lit.)
vapor pressure:
73 mmHg ( 20 °C)

CN¥647.86


Estimated to ship onJune 27, 2025Details


Request a Bulk Order

grade

ACS reagent

Quality Level

vapor density

3 (20 °C, vs air)

vapor pressure

73 mmHg ( 20 °C)

product line

SAFC Hitech®

Assay

≥99.5%

form

liquid

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

dilution

(for analytical testing)

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Show Differences

1 of 4

This Item
SML0493SML3153SML1878
AMG517 ≥98% (HPLC)

SML2717

AMG517

AMG 487 ≥98% (HPLC)

SML3153

AMG 487

GNF-1331 ≥98% (HPLC)

SML1878

GNF-1331

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear (warmed)

color

white to beige

color

white to beige

color

white to beige

color

white to beige

General description

Ethyl acetate, a carboxylate ester, is bio-friendly organic solvent with a wide range of industrial applications.[1] Its synthesis by reactive distillation[2][3] and by acceptorless dehydrogenative dimerization of ethanol has been explored.[4] Its utility as a less toxic alternative to diethyl ether in the formalin-ether (F-E) sedimentation procedure for intestinal parasites has been investigated.[5] Its ability as an acyl acceptor in the immobilized lipase-mediated preparation of biodiesel from crude vegetable oils has been examined.[6] The complete degradation of ethyl acetate to CO2 using manganese octahedral molecular sieve (OMS-2) has been investigated.[7]

Application

Ethyl acetate may be used in the following processes:
  • Preparation of thin films of TiO2 (titanium dioxide) on glass.[8]
  • As an extraction medium in the multiresidue analysis of pesticide residues in fruit and vegetables.[9]
  • Acetylation of primary amines to form amides in the presence of dimethyltin(IV) acetic acid distannoxane.[10]

Legal Information

SAFC Hitech is a registered trademark of Sigma-Aldrich Co. LLC

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Target Organs

Central nervous system

Supplementary Hazards

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

24.8 °F - closed cup

Flash Point(C)

-4 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Christer Jansson et al.
Journal of chromatography. A, 1023(1), 93-104 (2004-02-06)
A new multi-residue method for determination of pesticide residues in a wide variety of fruit and vegetables, using the National Food Administration (NFA) ethyl acetate extraction and determination by means of LC-MS/MS, is presented. The method includes pesticides normally detected
Perspectives for the biotechnological production of ethyl acetate by yeasts.
Loser C, et al.
Applied Microbiology and Biotechnology, 98(12), 5397-5415 (2014)
Manganese oxide OMS-2 as an effective catalyst for total oxidation of ethyl acetate.
Gandhe AR, et al.
Applied Catalysis. B, Environmental, 72(1), 129-135 (2007)
Catalytic Acetylation Amines with Ethyl Acetate.
Camacho-Camacho C, et al.
Main Group Metal Chemistry, 31(1-2), 13-20 (2008)
Investigation of ethyl acetate reactive distillation process.
Kenig EY, et al.
Chemical Engineering Science, 56(21), 6185-6193 (2001)

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