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Supelco

Farnesol

analytical standard, mixture of isomers, stabilized

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Synonym(s):
3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol
Linear Formula:
(CH3)2C=CHCH2CH2C(CH3)=CHCH2CH2C(CH3)=CHCH2OH
CAS Number:
4602-84-0
Molecular Weight:
222.37
Beilstein:
1763926
MDL number:
MFCD00002918
UNSPSC Code:
85151701
PubChem Substance ID:
329756337
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥95.0% (GC)

shelf life

limited shelf life, expiry date on the label

contains

α-tocopherol (synthetic stabilizer)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.488-1.492
n20/D 1.489 (lit.)

bp

149 °C/4 mmHg (lit.)

density

0.886 g/mL at 20 °C (lit.)

application(s)

cleaning products
cosmetics
environmental
flavors and fragrances
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C/C(CC/C=C(C)/CCC=C(C)C)=C\CO

InChI

1S/C15H26O/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-16/h7,9,11,16H,5-6,8,10,12H2,1-4H3/b14-9+,15-11+

InChI key

CRDAMVZIKSXKFV-YFVJMOTDSA-N

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General description

Farnesol is a sesquiterpenoid, acting as a quorum-sensing molecule that inhibits filamentation in Candida albicans. It can exhibit chemotherapeutic activity toward pancreatic and other cancers.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sensitization of Staphylococcus aureus and Escherichia coli to Antibiotics by the Sesquiterpenoids Nerolidol, Farnesol, Bisabolol, and Apritone.
Brehm-Stecher FB and Johnson AE
Antimicrobial Agents and Chemotherapy, 47(10), 3357?3360-3357?3360 (2003)
Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
DYB, et al.
Anticancer Research, 22(10), 3127-3134 (2002)
Inhibition of Candida albicans Biofilm Formation by Farnesol, a Quorum-Sensing Molecule.
Ramage G, et al.
Applied and Environmental Microbiology, 68(11), 5459?5463-5459?5463 (2002)
Taísa Magnani Dinamarco et al.
Biochemical Society transactions, 39(5), 1544-1548 (2011-09-23)
FOH (farnesol), a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, has been shown to inhibit proliferation and induce apoptosis. We have been using Aspergillus nidulans and FOH as a model system and cell death stimulus, respectively, aiming to understand
EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium.
Takamitsu Matsuzawa et al.
The Journal of investigative dermatology, 134(4), 1158-1161 (2014-01-05)
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