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Merck
CN

42910

Diphenylcyclopropenone

purum, ≥98.0% (HPLC)

Synonym(s):

DPC

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About This Item

Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
EC Number:
212-948-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
608049
MDL number:
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InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

grade

purum

assay

≥98.0% (HPLC)

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Leena M Koulu et al.
The Journal of investigative dermatology, 130(11), 2578-2582 (2010-07-09)
Polymorphic light eruption (PLE) is a common skin disorder provoked by exposure to UVR. Its clinical symptoms resemble those of a contact allergic reaction. PLE is generally considered a T-cell-mediated autoimmune reaction toward a yet unidentified antigen formed in UVR-exposed
Stamatis Gregoriou et al.
Mediators of inflammation, 2010, 928030-928030 (2010-03-20)
Alopecia areata, a disease of the hair follicles with multifactorial etiology and a strong component of autoimmune origin, has been extensively studied as far as the role of several cytokines is concerned. So far, IFN-gamma, interleukins, TNF-alpha, are cytokines that
Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of
Abdullah Alkhalifah et al.
Journal of the American Academy of Dermatology, 62(2), 191-202 (2010-02-02)
Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the
Nannie Bangsgaard et al.
Contact dermatitis, 63(1), 10-14 (2010-07-06)
It is uncertain whether polysensitized patients acquire multiple allergies only because of a high degree of exposure to environmental allergens, or because of being highly susceptible to developing contact allergy. The aim of this study was to investigate and compare

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