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42910

Sigma-Aldrich

Diphenylcyclopropenone

purum, ≥98.0% (HPLC)

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Synonym(s):
DPC
Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

grade

purum

Assay

≥98.0% (HPLC)

mp

118-122 °C (lit.)
118-122 °C

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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Signal Word

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Hazard Statements

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of
Abdullah Alkhalifah et al.
Journal of the American Academy of Dermatology, 62(2), 191-202 (2010-02-02)
Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the
Nannie Bangsgaard et al.
Contact dermatitis, 63(1), 10-14 (2010-07-06)
It is uncertain whether polysensitized patients acquire multiple allergies only because of a high degree of exposure to environmental allergens, or because of being highly susceptible to developing contact allergy. The aim of this study was to investigate and compare
Leena M Koulu et al.
The Journal of investigative dermatology, 130(11), 2578-2582 (2010-07-09)
Polymorphic light eruption (PLE) is a common skin disorder provoked by exposure to UVR. Its clinical symptoms resemble those of a contact allergic reaction. PLE is generally considered a T-cell-mediated autoimmune reaction toward a yet unidentified antigen formed in UVR-exposed
N Bangsgaard et al.
Clinical and experimental immunology, 165(3), 310-317 (2011-06-15)
An inverse relation between contact allergy and autoimmune diseases is suggested from epidemiological studies. The aim of this study was to investigate susceptibility and reactivity in patients with psoriasis, patients with diabetes and healthy controls in an experimental sensitization study.

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