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Key Documents

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42754

Supelco

Ginsenoside Rk1

analytical standard

Synonym(s):

(3β, 12β)-12-Hydroxydammara-20,24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
494753-69-4
Molecular Weight:
767.00
MDL number:
MFCD28124355
UNSPSC Code:
85151701
PubChem Substance ID:
329756264
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

Assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

format

neat

storage temp.

2-8°C

SMILES string

CC1(C)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@@]4(C)[C@@]1([H])CC[C@]5(C)[C@]4([H])C[C@@H](O)[C@@]6([H])[C@@]5(C)CC[C@@]6(C(CCC=C(C)C)=C)[H]

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10,23-38,43-50H,3,9,11-20H2,1-2,4-8H3/t23-,24-,25-,26-,27+,28-,29+,30

InChI key

KWDWBAISZWOAHD-MHOSXIPRSA-N

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Show Differences

1 of 4

This Item
466190T119945979
邻甲基苯胺 purum p.a., ≥99.5% (GC)

89610

邻甲基苯胺

邻甲基苯胺 98%

466190

邻甲基苯胺

邻甲苯胺 溶液 0.6 M in glacial acetic acid, contains thiourea as stabilizer

T1199

邻甲苯胺 溶液

邻甲基苯胺 analytical standard

45979

邻甲基苯胺

assay

≥99.5% (GC)

assay

98%

assay

-

assay

-

solubility

H2O: slightly soluble

solubility

H2O: slightly soluble

solubility

-

solubility

H2O: slightly soluble

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

-

form

-

mp

−28 °C (lit.)

mp

−28 °C (lit.)

mp

-

mp

−28 °C (lit.)

density

1.008 g/mL at 25 °C (lit.)

density

1.008 g/mL at 25 °C (lit.)

density

-

density

1.008 g/mL at 25 °C (lit.)

General description

Ginsenoside Rk1 is the major bioactive component isolated from heat-processed Panax ginseng Meyer (ginseng) plants. It is a monomeric compound that has been reported to exhibit anti-inflammatory, anti-allergic, and anti-tumor properties and is utilized for the treatment of cancer and diabetes mellitus.[1][2]

Application

Ginsenoside Rk1 may be used as an analytical reference standard for the determination of the analyte in Panax ginseng preparations[3][4] and Chinese medicine formula Sheng-Mai San (SMS) and rat plasma samples (post administration of SMS)[5] by chromatography techniques.

Other Notes

This compound is commonly found in plants of the genus: panax

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCK3489
    BCCK9682
    BCCD5860
    BCCD5721
    BCCB9283

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    Anti-tumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis
    Kim YJ, et al.
    Biological & Pharmaceutical Bulletin, 31(5), 826-830 (2008)
    Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264. 7 cells by inhibiting the Jak2/Stat3 pathway
    Qian YU, et al.
    Chinese Journal of Natural Medicines, 15(10), 751-757 (2017)
    Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography
    Park HW, et al.
    Journal of ginseng research, 37(4), 457-457 (2013)
    Identification of multiple constituents in the traditional Chinese medicine formula Sheng-Mai San and rat plasma after oral administration by HPLC-DAD-MS/MS
    Wang YH, etal.
    Journal of Pharmaceutical and Biomedical Analysis, 54(5), 1110-1127 (2011)
    Simultaneous quantification of 14 ginsenosides in Panax ginseng CA Meyer (Korean red ginseng) by HPLC-ELSD and its application to quality control.
    Kim NS, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 45(1), 164-170 (2007)

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