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Merck
CN

41716

N,N-Dimethyltrimethylsilylamine

Selectophore

Synonym(s):

(Dimethylamino)trimethylsilane, N-(Trimethylsilyl)dimethylamine, TMSDMA

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About This Item

Linear Formula:
(CH3)3SiN(CH3)2
CAS Number:
Molecular Weight:
117.26
EC Number:
218-222-3
UNSPSC Code:
26111700
PubChem Substance ID:
Beilstein/REAXYS Number:
1731861
MDL number:
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InChI key

KAHVZNKZQFSBFW-UHFFFAOYSA-N

InChI

1S/C5H15NSi/c1-6(2)7(3,4)5/h1-5H3

SMILES string

CN(C)[Si](C)(C)C

description

for ion-selective electrodes

product line

Selectophore

refractive index

n20/D 1.397 (lit.)

bp

84 °C (lit.)

density

0.732 g/mL at 25 °C (lit.)

Quality Level

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Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameCorrosion

signalword

Danger

Storage Class

4.3 - Hazardous materials which set free flammable gases upon contact with water

wgk

WGK 3

flash_point_f

10.4 °F - closed cup

flash_point_c

-12 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - Water-react. 1

Regulatory Information

危险化学品
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James P. Landers
Handbook of Capillary Electrophoresis, 428-428 (1996)
Brian Roland Larsen et al.
Glia, 62(4), 608-622 (2014-02-01)
Network activity in the brain is associated with a transient increase in extracellular K(+) concentration. The excess K(+) is removed from the extracellular space by mechanisms proposed to involve Kir4.1-mediated spatial buffering, the Na(+)/K(+)/2Cl(-) cotransporter 1 (NKCC1), and/or Na(+)/K(+)-ATPase activity.
Zhuo Luan et al.
Experimental neurology, 261, 791-801 (2014-09-11)
The activity of Na(+)/K(+)-ATPase establishes transmembrane ion gradients and is essential to cell function and survival. Either dysregulation or deficiency of neuronal Na(+)/K(+)-ATPase has been implicated in the pathogenesis of many neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and
Brian Roland Larsen et al.
The Journal of physiology, 597(2), 583-597 (2018-10-26)
Neuronal activity induces fluctuation in extracellular space volume, [K+ ]o and pHo , the management of which influences neuronal function The neighbour astrocytes buffer the K+ and pH and swell during the process, causing shrinkage of the extracellular space In
Trine Lisberg Toft-Bertelsen et al.
Glia, 69(1), 28-41 (2020-06-09)
The mammalian brain consists of 80% water, which is continuously shifted between different compartments and cellular structures by mechanisms that are, to a large extent, unresolved. Aquaporin 4 (AQP4) is abundantly expressed in glia and ependymal cells of the mammalian

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