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Key Documents

Safety Information

402788

Sigma-Aldrich

Acetaldehyde

ACS reagent, ≥99.5%

Synonym(s):

Ethanal

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5 MG
CN¥1,978.95
25 MG
CN¥6,372.41

CN¥1,978.95


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5 MG
CN¥1,978.95
25 MG
CN¥6,372.41

About This Item

Linear Formula:
CH3CHO
CAS Number:
Molecular Weight:
44.05
Beilstein:
505984
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39021102
PubChem Substance ID:
NACRES:
NA.21

CN¥1,978.95


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biological source

synthetic

Quality Level

grade

ACS reagent

vapor density

1.52 (vs air)

vapor pressure

14.63 psi ( 20 °C)

Assay

≥99.5%

form

liquid

autoignition temp.

365 °F

expl. lim.

60 %

impurities

≤0.008 meq/g Titr. acid

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MXRPWRSPZAMXRPWRSPUKMXRPWRSPBR
packaging

pkg of 1 ea

packaging

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packaging

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packaging

pkg of 1 ea

manufacturer/tradename

Milliflex®

manufacturer/tradename

Milliflex®

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Milliflex®

manufacturer/tradename

Milliflex®

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

technique(s)

Rapid Sterility Testing: suitable

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

application(s)

bioburden testing
pharmaceutical
sterility testing

General description

Acetaldehyde is an industrially important solvent used as an intermediate for the synthesis of a wide range of compounds. On oxidation it forms acetic acid and ethanol on reduction.[1] The interaction of Criegee intermediate (CH2OO) with acetaldehyde has been measured.[2] Its effect as a neuroactive agent has been studied.[3] Alkynylation reaction of acetaldehyde by asymmetric catalysis has been reported.[4]

Application

Acetaldehyde may be used in the synthesis of 1,3-diamines by one-pot cross double-Mannich reaction[5] and β-amino aldehydes by proline-catalyzed Mannich reaction.[6]

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

-38.0 °F - closed cup

Flash Point(C)

-38.89 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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    Direct measurement of Criegee intermediate (CH2OO) reactions with acetone, acetaldehyde, and hexafluoroacetone.
    Taatjes CA, et al.
    Physical Chemistry Chemical Physics, 14(30), 10391-10400 (2012)
    Proline-catalysed Mannich reactions of acetaldehyde.
    Yang JW, et al.
    Nature, 452(7186), 453-455 (2008)
    One-pot cross double-Mannich reaction of acetaldehyde catalyzed by a binaphthyl-based amino sulfonamide.
    Kano T, et al.
    Chemical Communications (Cambridge, England), 49(11), 1118-1120 (2013)
    Eagleson M.
    Concise Encyclopedia Chemistry, 4-4 (1994)
    Asymmetric Catalytic Alkynylation of Acetaldehyde: Application to the Synthesis of (+)-Tetrahydropyrenophorol.
    Trost BM and Quintard A.
    Angewandte Chemie (International Edition in English), 51(27), 6704-6708 (2012)

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