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37918

Supelco

4-Epitetracycline hydrochloride

VETRANAL®, analytical standard

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Synonym(s):
4-epi-Tetracycline hydrochloride
Empirical Formula (Hill Notation):
C22H24N2O8 · HCl
CAS Number:
23313-80-6
Molecular Weight:
480.90
MDL number:
MFCD00865028
UNSPSC Code:
41116107
PubChem Substance ID:
329755726
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

−20°C

SMILES string

Cl.CN(C)[C@@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)cccc4[C@@]3(C)O

InChI

1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15+,21+,22-;/m0./s1

InChI key

XMEVHPAGJVLHIG-DXDJYCPMSA-N

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General description

4-Epitetracycline hydrochloride is found to be a degradation product of tetracyclines, used in veterinary therapy.
Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H361fd

Hazard Classifications

Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Toxicity of tetracyclines and tetracycline degradation products to environmentally relevant bacteria, including selected tetracycline-resistant bacteria
Halling-S?rensen.B, et al.
Archives of Environmental Contamination and Toxicology, 42, 263-271 (2002)
Mohitosh Maiti et al.
Bioorganic & medicinal chemistry letters, 22(4), 1709-1711 (2012-01-20)
Over-expressions of miRNAs are being increasingly linked with many diseases including different types of cancer. In this study, the role of some known small molecular therapeutics has been investigated for their ability to bind with the pre-miRNA target (hsa-mir-155) and

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