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Safety Information

37017

Supelco

Fumagillin solution

~100 μg/mL in acetonitrile, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C26H34O7
CAS Number:
23110-15-8
Molecular Weight:
458.54
EC Number:
200-835-2
UNSPSC Code:
85151701
NACRES:
NA.24

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

~100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@@]3(C)O[C@@H]3C\C=C(\C)C)OC(=O)\C=C\C=C\C=C\C=C\C(O)=O

InChI

1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20?,23-,24-,25+,26+/m1/s1

InChI key

NGGMYCMLYOUNGM-IJIYPQOHSA-N

General description

Fumagillin is an antibiotic obtained by the fermentation of certain strains of Aspergillus fumigatus with potent amoebicidal action.

Application

Fumagillin may be used as an analytical reference standard for the quantification of the analyte in honey samples and technical materials using various chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

Regulatory Information

高风险级别生物产品--毒素类产品
危险化学品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH9705
BCCF3790
BCCB8671
BCBS6529V

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Patrícia M Carvalho et al.
Frontiers in chemistry, 6, 237-237 (2018-07-11)
Over the years, the scientific importance of nanoparticles for biomedical applications has increased. The high stability and biocompatibility, together with the low toxicity of the nanoparticles developed lead to their use as targeted drug delivery systems, bioimaging systems, and biosensors.
Trace analysis of fumagillin in honey by liquid chromatography-diode array-electrospray ionization mass spectrometry
Nozal.JM, et al.
Journal of Chromatography A, 1190(1-2), 224-231 (2008)
Determination of fumagillin by high performance liquid chromatography
Brackett.MJ, et al.
Journal of Agricultural and Food Chemistry, 36(4), 762-764 (1988)
Yujin Park et al.
Anticancer research, 37(8), 4139-4146 (2017-07-26)
Eribulin mesylate, also called Halaven® (HAL), was recently developed as a microtubule-targeting drug and is used in the clinic for resistant or metastatic cancer. Previously, we showed that P-glycoprotein (P-gp)-overexpressing KBV20C oral cancer cells are highly resistant to HAL compared
Lina Wu et al.
International journal of nanomedicine, 15, 7377-7395 (2020-10-17)
Fluorine-19 (19F) magnetic resonance (MR) molecular imaging is a promising noninvasive and quantitative molecular imaging approach with intensive research due to the high sensitivity and low endogenous background signal of the 19F atom in vivo. Perfluorocarbons (PFCs) have been used
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