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Azaperone

VETRANAL®, analytical standard

Synonym(s):

1-(4-Fluorophenyl)-4-(4-(2-pyridinyl)-1-piperazinyl)-1-butanone, 4′-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone

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About This Item

Empirical Formula (Hill Notation):
C19H22FN3O
CAS Number:
1649-18-9
Molecular Weight:
327.40
EC Number:
216-715-8
MDL number:
MFCD00866692
UNSPSC Code:
41116107
PubChem Substance ID:
329754908
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3ccccn3

InChI

1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2

InChI key

XTKDAFGWCDAMPY-UHFFFAOYSA-N

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General description

Azaperone (AZN) is a butyrophenone neuroleptic drug, used as a tranquilizer in veterinary medicine.

Application

Azaperone may be used as an analytical reference standard for the determination of the analyte in animal kidneys and blood meal by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG2974
BCCG6128
BCBT9584
BCBT7957
SZBD338XV

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Patrice M Mich et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 39(3), 480-487 (2008-09-27)
Chemical immobilization of wildlife often includes opioids or cyclohexamines. These substances are problematic as a result of their required storage, handling, and record-keeping protocols. A potentially useful alternative sedation protocol includes a combination of butorphanol, azaperone, and medetomidine (BAM: 0.43
T J Portas
Australian veterinary journal, 82(9), 542-549 (2004-10-14)
Captive rhinoceros species are most frequently sedated and/or anaesthetised with the potent opioid, etorphine hydrochloride in combination with an alpha-2 adrenoreceptor agonist or the butyrophenone, azaperone. Carfentanil citrate based combinations have also been used to a lesser extent. In recent
Gregorio Mentaberre et al.
Research in veterinary science, 88(3), 531-535 (2009-12-17)
The physical capture of wild ungulates is performed for different purposes when anaesthesia in field conditions is not possible or advisable. The use of tranquilizers may contribute to improved welfare of captured animals. We studied the effect of haloperidol and
G Mentaberre et al.
Journal of wildlife diseases, 46(3), 923-928 (2010-08-07)
We investigated the effect of haloperidol and azaperone in drive-net captured Southern chamois (Rupicapra pyrenaica). Both tranquilizers have been successfully used in a wide range of wild species for reducing postcapture stress response. During 2005, 39 free-ranging chamois were captured
John H Dubinion et al.
Journal of hypertension, 28(7), 1466-1470 (2010-05-06)
We examined the role of central nervous system (CNS) endogenous melanocortin 3/4 receptors (MC3/4R) activity in controlling cardiovascular and metabolic functions in Sprague Dawley rats fed a high-fat diet (n = 6) for 10 months compared with rats fed a
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