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34131

Supelco

Nivalenol solution

100 μg/mL in acetonitrile, analytical standard

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Synonym(s):
3α,4β,7α, 15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one, NIV
Empirical Formula (Hill Notation):
C15H20O7
CAS Number:
23282-20-4
Molecular Weight:
312.32
EC Number:
200-835-2
MDL number:
MFCD00133673
UNSPSC Code:
85151701
PubChem Substance ID:
329754837
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

SMILES string

[H][C@]12O[C@]3([H])[C@H](O)[C@@H](O)[C@@](C)([C@]34CO4)[C@@]1(CO)[C@H](O)C(=O)C(C)=C2

InChI

1S/C15H20O7/c1-6-3-7-14(4-16,11(20)8(6)17)13(2)10(19)9(18)12(22-7)15(13)5-21-15/h3,7,9-12,16,18-20H,4-5H2,1-2H3/t7-,9-,10-,11-,12-,13-,14-,15+/m1/s1

InChI key

UKOTXHQERFPCBU-XBXCNEFVSA-N

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General description

Certan Vial
Nivalenol is a potential trichothecene mycotoxin, produced by Fusarium nivale., Genotoxicity of nivalenol is evaluated by alkaline single-cell gel electrophoresis assay.
Nivalenol is a secondary metabolite produced by Fusarium species, which is a plant pathogenic fungus of wheat and other cereals.

Application

Nivalenol was used as standard to investigate in vitro mycotoxin binding of deoxynivalenol and nivalenol by adsorbent materials (activated carbon).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

Flash Point(F)

35.6 °F

Flash Point(C)

2 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
高风险级别生物产品--毒素类产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of nivalenol and deoxynivalenol by liquid chromatography/atmospheric pressure photoionization mass spectrometry
Tanaka H, et al.
Rapid Communications in Mass Spectrometry, 23(19), 3119- 3124 (2009)
Alaleh Zoghi et al.
Mini reviews in medicinal chemistry, 14(1), 84-98 (2013-12-18)
Removal of toxic metals and toxins using microbial biomass has been introduced as an inexpensive, new promising method on top of conventional methods for decontamination of food, raw material and concentrated. In this article the potential application of lactic acid
S Tsuda et al.
Mutation research, 415(3), 191-200 (1998-08-26)
We tested the genotoxicity of nivalenol (NIV), a potent toxic trichothecene from Fusarium nivale, in cultured CHO cells and in several mouse organs and tissues (liver, kidney, thymus, bone marrow and mucosa of stomach, jejunum, and colon) using the alkaline
Jungkwan Lee et al.
Applied and environmental microbiology, 78(7), 2161-2167 (2012-01-31)
Fusarium graminearum (Gibberella zeae) is an important pathogen of wheat, maize, barley, and rice in South Korea, and harvested grain often is contaminated with trichothecenes such as deoxynivalenol and nivalenol. In this study, we examined 568 isolates of F. graminearum
Tadahiro Suzuki et al.
Journal of agricultural and food chemistry, 60(37), 9519-9527 (2012-08-18)
Type B trichothecenes, deoxynivalenol (DON) and nivalenol (NIV), are secondary metabolites of Fusarium species and are major pollutants in food and feed products. Recently, the production trend of their derivatives, 3-acetyldeoxynivalenol (3-AcDON), 15-acetyldeoxynivalenol (15-AcDON), and 4-acetylnivalenol (4-AcNIV or fusarenon-X), has
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