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Diclazuril

VETRANAL®, analytical standard

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Synonym(s):
2,6-Dichloro-α-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrile
Empirical Formula (Hill Notation):
C17H9Cl3N4O2
CAS Number:
101831-37-2
Molecular Weight:
407.64
MDL number:
MFCD00867203
UNSPSC Code:
41116107
PubChem Substance ID:
329754784
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Clc1ccc(cc1)C(C#N)c2c(Cl)cc(cc2Cl)N3N=CC(=O)NC3=O

InChI

1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)

InChI key

ZSZFUDFOPOMEET-UHFFFAOYSA-N

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Application

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H361d,H373

Hazard Classifications

Repr. 2 - STOT RE 2

Target Organs

Lungs,Liver,lymph node

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Xiaojiong Shen et al.
Veterinary parasitology, 185(2-4), 290-295 (2011-11-15)
Eimeria tenella (E. tenella) is one of the most virulent pathogens of coccidiosis. In apicomplexan parasites, Hsp90 (Heat shock protein 90) is essential for the invasion and survival in host cells. In this study, the effect of diclazuril, an effective
Assessing the effect of diclazuril on the intestinal absorptive capacity of broilers infected with experimental coccidiosis, using d-xylose absorption test.
H Nodeh et al.
Journal of veterinary pharmacology and therapeutics, 31(3), 265-267 (2008-05-13)
C Le Sueur et al.
Parasitology research, 104(5), 1157-1162 (2008-12-17)
A field study was conducted to evaluate the effect of a single oral treatment with 20 mg/kg body weight (BW) of toltrazuril (Baycox 5% suspension)--TOL--in comparison to a single oral treatment with 1 mg/kg BW of diclazuril (Vecoxan suspension orale
Zuhao Shi et al.
Se pu = Chinese journal of chromatography, 27(3), 303-307 (2009-10-07)
The effects of four pretreatment methods (acetonitrile extraction-evaporation concentration, acetonitrile extraction-solid phase extraction (SPE), matrix solid-phase dispersion (MSPD) extraction and MSPD-SPE) for the simultaneous analysis of diclazuril and toltrazuril residues in chicken tissues were compared. The average recovery of 70%
Bian-hua Zhou et al.
Parasitology research, 112(4), 1771-1780 (2013-02-19)
Screening the anticoccidial drug targets is very important for developing novel drugs and revealing the molecular basis of drug resistance in coccidia. Due to high effectivity and safety, diclazuril was used widely in the poultry industry. To assess the roles
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