All Photos(2)
Synonym(s):
2-(1-Methyl-5-nitro-1H-imidazol-2-yl)propan-2-ol, Hydroxy-ipronidazole, IPZOH
Empirical Formula (Hill Notation):
C7H11N3O3
CAS Number:
Molecular Weight:
185.18
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cn1c(cnc1C(C)(C)O)[N+]([O-])=O
InChI
1S/C7H11N3O3/c1-7(2,11)6-8-4-5(9(6)3)10(12)13/h4,11H,1-3H3
InChI key
DTHPMNDYKOSVFR-UHFFFAOYSA-N
Related Categories
General description
Ipronidazole-OH is a metabolite of nitroimidazole antibiotics, used in veterinary medicine to combat anaerobic bacterial and parasitic infections.
Application
Ipronidazole-OH may be used as a reference standard in the determination of nitroimidazole drug and its corresponding hydroxy metabolites in aquaculture tissue by ultra-high performance liquid chromatography coupled to tandem mass spectrometry.
Ipronidazole-OH may be used as an analytical reference standard for the determination of the analyte in:
- Cosmetics using high-performance liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS).
- Aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Recommended products
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
related product
Product No.
Description
Pricing
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry.
Gadaj A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 960(6), 105-115 (2014)
Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization-tandem mass spectrometry.
Meng S-X, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 97(6), 1538-1545 (2014)
Kamila Mitrowska et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 573-581 (2016-11-15)
Nitroimidazoles are not authorised for the treatment of honey bees in the European Union. However, they can be found in honey largely because they are illegally used in apiculture for the treatment of Nosema. The aim of the study was
Simone Moretti et al.
Analytica chimica acta, 1032, 56-67 (2018-08-26)
A multiclass screening method to detect fifty-three forbidden substances by liquid-chromatography coupled to hybrid high-resolution mass spectrometry (LC-Q-Orbitrap) was developed and validated in bovine bile and urine. Eight classes of compounds were included in the method's scope (β-agonists, corticosteroids, nitroimidazoles
Chengfei Wang et al.
Food chemistry, 334, 127598-127598 (2020-07-25)
A multi-residue method has been developed for the identification and quantification of 78 compounds from seven different classes of veterinary drugs in eggs. This method was based on dispersive solid phase extraction where mixed-mode cation exchange sorbent was used to
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