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Ethopabate

VETRANAL®, analytical standard

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Synonym(s):
Methyl 4-acetamido-2-ethoxybenzoate, Ethopabate, Ethyl pabate
Empirical Formula (Hill Notation):
C12H15NO4
CAS Number:
59-06-3
Molecular Weight:
237.25
Beilstein:
2808914
EC Number:
200-414-3
MDL number:
MFCD00075809
UNSPSC Code:
41116107
PubChem Substance ID:
329754735
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCOc1cc(NC(C)=O)ccc1C(=O)OC

InChI

1S/C12H15NO4/c1-4-17-11-7-9(13-8(2)14)5-6-10(11)12(15)16-3/h5-7H,4H2,1-3H3,(H,13,14)

InChI key

GOVWOKSKFSBNGD-UHFFFAOYSA-N

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General description

Ethopabate is an antibiotic used as a coccidiostat in poultry feeds.

Application

Ethopabate may be used as a reference standard in the determination of ethopabate in feed samples using solid phase extraction with high performance liquid chromatography (SPE-HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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C A Kan et al.
Tijdschrift voor diergeneeskunde, 114(2), 76-82 (1989-01-15)
Amprolium may be used as a coccidiostat in rearing hens and is a therapeutical agent used in laying hens. As a result of cross contamination, low amprolium levels may occur in feed. Feed containing a concentration of amprolium ranging from
Illegal use of Amprol-Plus for game.
O Swarbrick
The Veterinary record, 127(12), 315-315 (1990-09-22)
The treatment of coccidiosis: studies on the sensitivity of recent field isolates of Eimeria acervulina type to anticoccidial drugs given in the drinking water.
H D Chapman
Journal of comparative pathology, 92(2), 213-218 (1982-04-01)
H D Chapman
Research in veterinary science, 46(3), 419-420 (1989-05-01)
Treatment with toltrazuril, sulphaquinoxaline/pyrimethamine and amprolium/ethopabate prevented mortality in chickens infected with field isolates of Eimeria tenella. Amprolium/ethopabate was the most effective drug in reducing lesions caused by the parasites. Few oocysts of E tenella were produced in birds medicated
L R Schronk et al.
Journal - Association of Official Analytical Chemists, 60(5), 1048-1050 (1977-09-01)
A high pressure liquid chromatographic (HPLC) method is described for determining ethopabate in poultry feeds. Feed samples containing ethopabate are finely ground, extracted 30 min by sonification with methanol-water (80 + 20), and filtered. The extract is cleaned up on
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