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33994

Supelco

Altrenogest

VETRANAL®, analytical standard

Synonym(s):

17-α-Allyl-17-β-hydroxyoestra-4,9,11-trien-3-one, Allyltrenbolone, Regumate

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About This Item

Empirical Formula (Hill Notation):
C21H26O2
CAS Number:
850-52-2
Molecular Weight:
310.43
EC Number:
212-703-1
MDL number:
MFCD00867855
UNSPSC Code:
41116107
PubChem Substance ID:
329754733
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)CCC3=C1C=C[C@@]4(C)[C@@]2([H])CC[C@@]4(O)CC=C

InChI

1S/C21H26O2/c1-3-10-21(23)12-9-19-18-6-4-14-13-15(22)5-7-16(14)17(18)8-11-20(19,21)2/h3,8,11,13,18-19,23H,1,4-7,9-10,12H2,2H3/t18-,19+,20+,21+/m1/s1

InChI key

VWAUPFMBXBWEQY-ANULTFPQSA-N

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General description

Altrenogest can be called as a steroid or a progestational drug, which finds applications in breeding. It can mainly be used to control or suppress the condition of estrus in horses.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

H301,H360FD,H373,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 1 - Repr. 1B - STOT RE 2 Oral

Target Organs

Immune system,Adrenal gland

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCJ8084
BCBW6632
SZBD099XV
SZBA074XV
SZBA074X

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Conrad Willmann et al.
Theriogenology, 75(3), 421-428 (2010-12-15)
The treatment of early pregnant mares with a history of repeated early embryonic loss with the progestin altrenogest has become routine; however no controlled studies on the efficiency of altrenogest to prevent embryonic losses are available so far. In the
C Willmann et al.
Theriogenology, 76(1), 61-73 (2011-03-15)
A positive influence of altrenogest treatment on a retarded development of the conceptus around the beginning of placentation in mares older than 8 years could be recently demonstrated. In the present study, effects of altrenogest treatment in early-pregnant mares on
Detection of altrenogest and its metabolites in post administration horse urine using liquid chromatography tandem mass spectrometry?increased sensitivity by chemical derivatisation of the glucuronic acid conjugate
Lampinen-Salomonsson M, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 833, 245-256 (2006)
Current Therapy in Equine Medicine (2009)
C S Bailey et al.
Theriogenology, 74(3), 402-412 (2010-04-27)
The objective was to determine if long-term treatment with trimethoprim sulfamethoxazole (antimicrobial), pentoxifylline (anti-inflammatory/anti-cytokine) and altrenogest (synthetic progestin), would improve pregnancy outcome in mares with experimentally induced placentitis. Seventeen normal, pregnant pony mares were enrolled in the study at 280-295
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