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Clorsulon

VETRANAL®, analytical standard

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Synonym(s):
4-Amino-6-(trichlorovinyl)-1,3-benzenedisulfonamide
Empirical Formula (Hill Notation):
C8H8Cl3N3O4S2
CAS Number:
60200-06-8
Molecular Weight:
380.66
EC Number:
262-100-2
MDL number:
MFCD00072006
UNSPSC Code:
41116107
PubChem Substance ID:
329754714
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

Nc1cc(\C(Cl)=C(\Cl)Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI

1S/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)

InChI key

QOVTVIYTBRHADL-UHFFFAOYSA-N

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General description

Clorsulon, is a benzene sulphonamide and a flukicide, which is found to be effective against the adult and immature form of liver fluke, Fasciola hepatica in cattle.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 3

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dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T A Morsy et al.
Journal of the Egyptian Society of Parasitology, 31(2), 373-379 (2001-08-02)
Five goats naturally infested with Sarcoptes scabiei, Psoroptes ovis and Bovicola caprae were treated with a combination of ivermectin and clorsulon. A subcutaneous injection in a dose of 1 ml/50 kg live weight was given. This provides dose levels of
T A Morsy et al.
Journal of the Egyptian Society of Parasitology, 31(1), 79-85 (2003-02-01)
Scabies infestation is a community health problem worldwide. This is particularly true in overcrowded and unhygienic areas. Seven dogs were experimentally infested with Sarcoptes scabiei freshly recovered from a patient. The dogs after infestation were treated with a mixture of
L Moll et al.
Veterinary parasitology, 91(1-2), 153-158 (2000-07-13)
In the winter of 1998/1999, sheep on a farm in the province of North Holland, The Netherlands, died from subacute and chronic liver fluke disease despite four previous treatments with triclabendazole (TCBZ). Faecal examinations of sheep and cattle on the
Shereen F Mossallam et al.
Journal of the Egyptian Society of Parasitology, 37(1), 171-188 (2007-06-22)
The efficacy of Clorsulon (CLS) against experimental schistosomiasis mansoni, using Praziquantel (PZQ) as a therapeutic control was evaluated. Swiss Albino mice were divided into infected non-treated control, PZQ-treated group given a single dose of 500 mg/kg four weeks post infection
M Meaney et al.
Parasitology research, 95(3), 201-212 (2005-01-13)
Three experiments have been carried out in vitro to determine the effect of oral and trans-tegumental uptake of clorsulon on the fine structure of the tegument and gut of Fasciola hepatica. Changes were assessed by transmission electron microscopy. In the
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