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33893

Supelco

Microcystin-LR solution

10 μg/mL in methanol, analytical standard

Synonym(s):

Cyanoginosin, Fast-death factor

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About This Item

Empirical Formula (Hill Notation):
C49H74N10O12
CAS Number:
101043-37-2
Molecular Weight:
995.17
EC Number:
200-659-6
MDL number:
MFCD01774058
UNSPSC Code:
41116107
PubChem Substance ID:
329754699
NACRES:
NA.24

grade

analytical standard

Quality Level

100

shelf life

limited shelf life, expiry date on the label

concentration

10 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

single component solution

storage temp.

−20°C

SMILES string

CO[C@@H](Cc1ccccc1)[C@@H](C)\C=C(C)\C=C\[C@@H]2NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](C)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)NC(=O)C(=C)N(C)C(=O)CC[C@@H](NC(=O)[C@H]2C)C(O)=O)C(O)=O

InChI

1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-31,34-38,40H,8,14,17,20-23,25H2,1-7,9-10H3,(H,53,64)(H,54,65)(H,55,62)(H,56,61)(H,57,63)(H,58,66)(H,67,68)(H,69,70)(H4,50,51,52)/b19-18+,27-24+/t28-,29-,30-,31+,34-,35-,36+,37-,38-,40+/m0/s1

InChI key

ZYZCGGRZINLQBL-GWRQVWKTSA-N

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General description

Microcystin-LR belongs to the group of cyclic heptapeptide metabolites called microcystins, produced by cyanobacterium (blue-green algae) Microcystis aeruginosa, and others.

Application

The analytical standard can also be used as follows:

  • Development of a paper immunosensor based on nanobiochar particles (nBC) and anti-microcystin-LR monoclonal antibodies (mAbs) for the identification of microcystin-LR in environmental water samples
  • Determination of microcystin-LR in tap water samples using a lateral flow immunochromatographic assay (LFICA) procedure based on molecularly imprinted polymers and enzyme-assisted color change approach
  • Fluorescence-based detection of microcystin-LR in tap water and serum samples by an aptasensor, constructed using single-walled carbon nanotubes (SWNTs) and dapoxyl fluorescent dye
  • Analysis of surface water samples for the detection of microcystin-LR using ultra high-performance liquid chromatography-mass spectrometry (UHPLC-MS) and high-performance liquid chromatography-variable wavelength-Ultraviolet Detector (HPLC-VW-UVD) methods
  • Determination of microcystin-LR in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

WGK

WGK 2

Flash Point(F)

51.8 °F

Flash Point(C)

11 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
高风险级别生物产品--毒素类产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM0441
BCCL6450
BCCK9887
BCCK2672
BCCJ1204

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Journal of lipid research, 58(12), 2348-2364 (2017-10-08)
Lipin-1 is a Mg
Macarena Pírez-Schirmer et al.
Analytical chemistry, 91(15), 9925-9931 (2019-07-11)
Here we present a new analytical method where immunoconcentration of the analyte is coupled to quantitative matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) analysis allowing in minutes the identification and highly sensitive quantitation of microcystins (MCs)
Keke Zhang et al.
Talanta, 185, 405-410 (2018-05-16)
This work reveals the deleterious effect of microcystin-LR (MC-LR) on the conformation of DNA and develops an electrochemical biosensor for detection of MC-LR. The biosensor is prepared by physically immobilizing calf thymus DNA (ctDNA) on gold electrode. In the presence
Laura García-Espín et al.
Ecotoxicology (London, England), 26(5), 658-666 (2017-04-07)
The ecological influence of cyanotoxins on aquatic biota remains unclear despite the numerous published references on toxicological and sanitary problems related with cyanophyte proliferation. The effects of microcystins and cyanophyte extracts on the photosynthesis of the algae that belong to
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