33880
AOZ-d4
VETRANAL®, analytical standard
Synonym(s):
3-Aminooxazolidin-2-one-d4, 4,4,5,5-Tetradeutero-3-amino-oxazolidin-2-one
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About This Item
Empirical Formula (Hill Notation):
C3H2D4N2O2
CAS Number:
Molecular Weight:
106.12
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
clinical testing
format
neat
mass shift
M+4
SMILES string
[2H]C1([2H])OC(=O)N(N)C1([2H])[2H]
InChI
1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2/i1D2,2D2
InChI key
KYCJNIUHWNJNCT-LNLMKGTHSA-N
Related Categories
General description
It is an isotopically labelled solution of AOZ, also known as 3-amino-2-oxazolidinone, a metabolite of the synthetic nitrofuran veterinary antibiotic― furazolidone.
Application
The analytical standard can be used as an internal standard for the following:
- Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry (MS/MS)
- Determination of four nitrofuran metabolites in a variety of food samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) following their extraction using a solid-phase microextraction (SPME) probe
- Simultaneous estimation of nitrofuran and chloramphenicol residues in animal-based food products using UHPLC, coupled with high-resolution mass spectrometry (HRMS)
- Development of a UHPLC-MS/MS-based method for the estimation of nitrofurans along with their metabolites in biological samples
- Liquid-liquid extraction of chloramphenicol, florfenicol, and nitrofuran metabolites from honey samples for their analysis by LC-MS/MS
- Estimation of nitrofuran metabolites in poultry muscle and eggs using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Analysis of nitrofuran metabolic residues in salt by liquid chromatography--tandem mass spectrometry
Pereira S.A, et al.
Analytica Chimica Acta, 514(1), 9-13 (2004)
Determination of nitrofuran metabolites in poultry muscle and eggs by liquid chromatography-tandem mass spectrometry
Finzi KJ, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 824(1-2), 30-35 (2005)
EunChae Ryu et al.
Environmental science and pollution research international, 28(6), 7551-7563 (2020-10-11)
A simplified method is described for reducing the analysis time of nitrofurans (NFs) and nitrofuran metabolites (NFMs) in the aquatic animals. Most existing HPLC-MS/MS methods are intended only for NFMs and are based on their fast metabolic transformations. We optimized
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