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Merck
CN

33211-M

Ethyl acetate

puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

Synonym(s):

EtOAc

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About This Item

Linear Formula:
CH3COOC2H5
CAS Number:
Molecular Weight:
88.11
UNSPSC Code:
12352108
NACRES:
NA.21
PubChem Substance ID:
EC Number:
205-500-4
Beilstein/REAXYS Number:
506104
MDL number:
Assay:
≥99.5% (GC)
Technique(s):
GC/GC: suitable
Bp:
76.5-77.5 °C (lit.)
Vapor pressure:
73 mmHg ( 20 °C)
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Product Name

Ethyl acetate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.5% (GC)

InChI key

XEKOWRVHYACXOJ-UHFFFAOYSA-N

InChI

1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

SMILES string

CCOC(C)=O

grade

ACS reagent
puriss. p.a.

agency

USP/NF
reag. ISO
reag. Ph. Eur.

vapor density

3 (20 °C, vs air)

vapor pressure

73 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

801 °F

expl. lim.

2.2-11.5 %, 38 °F

technique(s)

GC/GC: suitable

impurities

≤0.001% non-volatile matter
≤0.0045% free acid (as CH3COOH)
≤0.05% water (Karl Fischer)
≤0.1% ethanol (GC)
≤0.1% isobutylalcohol
≤0.1% methanol
≤0.1% methyl acetate

color

APHA: >10

refractive index

n20/D 1.3710-1.3730
n20/D 1.3720 (lit.)

bp

76.5-77.5 °C (lit.)

mp

−84 °C (lit.)

density

0.902 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.5 mg/kg
B: ≤0.02 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.1 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤0.5 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sn: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.1 mg/kg

suitability

passes test for reaction against H2SO4

format

neat

Quality Level

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Application

Ethyl acetate can be used as:     
  • A reactant to synthesize cinnamyl acetate via lipase-catalyzed transesterification reaction between ethyl acetate and cinnamyl alcohol.      
  • A reaction medium to synthesize solid electrolyte Li3PS4 by the reaction between Li2S and P2S5.      
  • A solvent in the synthesis of 6-O-acetyl glycosides via selective acetylation of carbohydrates in the presence of a catalytic amount of sulfuric acid. 6-O-acetyl glycoside derivatives are applicable as precursors for the synthesis of complex oligosaccharides.      
  • A reactant to prepare geranyl acetate by transesterification of geraniol.      
  • A green solvent in solid-phase peptide synthesis.

Features and Benefits

EtOAc is an environmentally safe solvent/reagent.

General description

Ethyl Acetate (EtOAc) is an organic compound with a characteristic sweet smell. It is commonly used as a coating solvent for paints, lacquers, and varnishes. It is also used as an extraction solvent and reagent in many pharmaceutical industries.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

26.6 °F - closed cup

flash_point_c

-3.00 °C - closed cup

Regulatory Information

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