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Merck
CN

32996

Sulfadimethoxine-d6

VETRANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12D6H8N4O4S
CAS Number:
Molecular Weight:
316.37
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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InChI key

ZZORFUFYDOWNEF-WFGJKAKNSA-N

SMILES string

[2H]C([2H])([2H])Oc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC([2H])([2H])[2H])n1

InChI

1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)/i1D3,2D3

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

mass shift

M+6

Quality Level

General description

Sulfadimethoxine-d6 is an isotopically labeled compound of sulfonamide antibiotics. It is typically utilized as an analytical standard in chromatographic determinations.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfadoxine-d6 may be used as an analytical standard for the determination of various sulfonamides in:
  • Wastewater samples by ultra-performance liquid chromatography-triple quadrupole-linear ion trap mass spectrometer (UPLC-QqLit-MS).
  • Fish samples as well as soil, sludge and manure samples by LC with tandem mass spectrometry (MS/MS).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

美国出口管控产品
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Simultaneous extraction of four classes of antibiotics in soil, manure and sewage sludge and analysis by liquid chromatography-tandem mass spectrometry with the isotope-labelled internal standard method.
Huang Y, et al.
Analytical Methods : Advancing Methods and Applications, 5(15), 3721-3731 (2013)
Multiresidue antimicrobial determination in Nile tilapia (Oreochromis Niloticus) cage farming by liquid chromatography tandem mass spectrometry.
Monteiro SH, et al.
Aquaculture (Amsterdam, Netherlands), 447, 37-43 (2015)
Evan Trofimchuk et al.
Journal of food science, 85(3), 736-743 (2020-02-06)
By utilizing the coffee-ring effect and microfluidic paper-based analytical devices (µPADs), this study improved the sensitivity of the determination of norfloxacin in four different food matrices. Micro-PADs in this study were fabricated by designing and embedding wax channels onto cellulose-based
Erhan Kenar et al.
Molecular & cellular proteomics : MCP, 13(1), 348-359 (2013-11-02)
Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require automated processing
Sérgio H Monteiro et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 51(12), 817-823 (2016-08-06)
The aim of this study was to investigate the relationship between antibiotic residues found in the muscle of cage-farm-raised Nile tilapia (Oreochromisniloticus), the occurrence of resistant bacteria, and the sanitary practices adopted by farmers in Ilha Solteira reservoir, Brazil. Nine

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